Loop Health vs Enhance MD
An in-depth comparison of two leading GLP-1 Providers
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Loop Health
Best for peptide and wellness membership with GLP-1s as one offeringStarting at $79/mo
Enhance MD
Best for lab-monitored compounded GLP-1 with mandatory video visitStarting at $49/mo
Side-by-Side Comparison
| Feature | Loop Health | Enhance MD |
|---|---|---|
| Overall Score | 6.8/10 | ✓8.6/10 |
| Starting Price | $79/mo | ✓$49/mo |
| Editorial Rating | 3.4 ★ /5 | ✓4.3 ★ /5 |
| Features | 6 features | 6 features |
| States Available | 0 | ✓39 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
Loop Health
Pros
- ✓Multi-product wellness platform — GLP-1 plus peptides, NAD+, coaching, bloodwork
- ✓Low membership entry point ($79/mo)
- ✓Annual plan includes monthly 'research credit' toward compounds
- ✓Explicit compounded-drug FDA disclaimer on-site
Cons
- ✗Per-dose GLP-1 drug pricing not transparent on public site (compounds billed separately by pharmacy)
- ✗States-served list not enumerated — only 'select U.S. states'
- ✗Platform explicitly 'is not a healthcare provider' — relies on independent provider network
- ✗No LegitScript number disclosed on homepage
Enhance MD
Pros
- ✓Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
- ✓Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
- ✓Three tiers, including a combined semaglutide + tirzepatide Elite plan ($322/mo) for patients plateaued on one GLP-1
- ✓Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
- ✓Low first-month intro pricing: $49 Core, $99 Advanced, $189 Elite
- ✓Unlimited clinician messaging and dose-adjustment support included
Cons
- ✗Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- ✗Not available in 10 states: AL, AR, GA, HI, LA, MS, MO, SC, TN, WV
- ✗Mandatory lab work adds 5–10 days to onboarding vs async-only competitors
- ✗No insurance accepted — cash pay, HSA/FSA eligible
- ✗Intro pricing resets to full tier rate after 30 days — the $49/$99/$189 figures aren't ongoing cost
Our Verdict
Enhance MD edges out Loop Health with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. Loop Health remains a solid alternative, especially if you're looking for peptide and wellness membership with GLP-1s as one offering.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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