HumeCare+ vs Enhance MD
An in-depth comparison of two leading GLP-1 Providers
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HumeCare+
Best for People who want GLP-1 weight loss with real-time body-composition tracking to protect muscleStarting at $199/mo
Enhance MD
Best for lab-monitored compounded GLP-1 with mandatory video visitStarting at $212/mo
Side-by-Side Comparison
| Feature | HumeCare+ | Enhance MD |
|---|---|---|
| Overall Score | 7.1/10 | ✓8.6/10 |
| Starting Price | ✓$199/mo | $212/mo |
| Editorial Rating | 3.6 ★ /5 | ✓4.3 ★ /5 |
| Features | ✓8 features | 6 features |
| States Available | 0 | ✓39 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
HumeCare+
What we like
- Pairs compounded semaglutide with continuous body-composition tracking (lose fat, preserve muscle)
- Includes a Hume Pod body-composition device at no extra cost
- From $199/mo, billed monthly, cancel anytime
- Backed by Hume Health, an established body-composition scale brand
- Clinician-prescribed and monitored with weekly tracking
Watch-outs
- Final medication pricing is gated behind an intake quiz
- Only semaglutide is shown on the marketing site (tirzepatide not confirmed)
- Prescribing medical group and pharmacy partner not named
- States of operation not published
- Not LegitScript-certified (no certification displayed)
Enhance MD
What we like
- Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
- Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
- Three tiers, including a combined semaglutide + tirzepatide Elite plan ($322/mo) for patients plateaued on one GLP-1
- Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
- Low first-month intro pricing: $49 Core, $99 Advanced, $189 Elite
- Unlimited clinician messaging and dose-adjustment support included
Watch-outs
- Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- Not available in 10 states: AL, AR, GA, HI, LA, MS, MO, SC, TN, WV
- Mandatory lab work adds 5–10 days to onboarding vs async-only competitors
- No insurance accepted — cash pay, HSA/FSA eligible
- Intro pricing resets to full tier rate after 30 days — the $49/$99/$189 figures aren't ongoing cost
Our Verdict
Enhance MD edges out HumeCare+ with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. HumeCare+ remains a solid alternative, especially if you're looking for People who want GLP-1 weight loss with real-time body-composition tracking to protect muscle.
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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