Helios Meds vs Vytora Health
An in-depth comparison of two leading GLP-1 Providers
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Helios Meds
Best for: Transparent low-cost compounded semaglutide from a LegitScript-approved telehealth provider
Visit Helios Meds →
Vytora Health
Best for: compounded or brand-name GLP-1 with named pharmacy partners, 50 states
Visit Vytora Health →Helios Meds and Vytora Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Helios Meds starts lower at $149.99/mo versus $150/mo, and Vytora Health edges ahead overall (8.4 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Helios Meds
Vytora Health
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What’s included
Helios Meds
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Vytora Health
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Helios Meds
7.0/10
Vytora Health
8.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Helios Meds | Vytora Health |
|---|---|---|
| Starting Price | ✓$149.99/mo | $150/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | 51 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Helios Meds
Helios Meds is a US telehealth provider based in Hockessin, Delaware offering physician-prescribed compounded GLP-1 medications for weight loss, with US board-certified physicians and LegitScript approval. Compounded semaglutide starts at $149.99/month and compounded tirzepatide at $349.97/month, with an online provider review and discreet shipping. Pricing is transparent; a public state list is not enumerated on the site.
Read our full Helios Meds review →About Vytora Health
Vytora Health is a 50-state-plus-DC telehealth platform offering compounded semaglutide and tirzepatide alongside brand-name Mounjaro and Zepbound, plus NAD+ and sermorelin peptides. It names its pharmacy partners publicly — Vials Pharmacy and Greenwich Biosciences — and discloses its operating physician group, uncommon transparency for the category. Compounded semaglutide runs $180/mo ($150 on a 3-month bundle) and tirzepatide $249/mo ($200 bundled).
Read our full Vytora Health review →Pros & Cons
Helios Meds
What we like
- Transparent compounded pricing: semaglutide from $149.99/month
- Compounded semaglutide and tirzepatide via online provider review
- LegitScript-approved with US board-certified physicians
- Discreet shipping
Watch-outs
- Compounded GLP-1s are not FDA-approved finished products
- Tirzepatide is relatively pricey at $349.97/month
- Public state list is not enumerated
- Cash-pay only — no insurance billing
Vytora Health
What we like
- All 50 states plus DC, with per-state video-vs-audio compliance disclosed
- Both compounded and brand-name options on one platform — uncommon
- LegitScript Approved and HIPAA compliant
- Pharmacy partners named publicly: Vials Pharmacy (TX) and Greenwich Biosciences
- Operating entity disclosed: Wasef Health, PC (Pinellas Park, FL)
- Competitive monthly pricing ($180 sema / $249 tirz) plus a 3-month bundle saving 17%
- Brand-name Mounjaro and Zepbound available at $1,399/mo for FDA-approved options
Watch-outs
- Brand-name Mounjaro/Zepbound at $1,399/mo is near retail — insured patients may do better via LillyDirect Self Pay ($449-$699/mo)
- Compounded tirzepatide at $249/mo is mid-market, above the $149-199 floor
- Dose tiers aren't broken out — 'all doses included' means low-dose patients pay the same as high-dose
- Initial consultation cost not shown on the public pricing page
- Limited per-prescriber state licensure detail
Our Verdict
Vytora Health edges out Helios Meds with a higher overall score of 8.4/10 and is particularly strong for compounded or brand-name GLP-1 with named pharmacy partners, 50 states. Helios Meds remains a solid alternative, especially if you're looking for Transparent low-cost compounded semaglutide from a LegitScript-approved telehealth provider.
Choose Helios Meds if…
You want Transparent low-cost compounded semaglutide from a LegitScript-approved telehealth provider and a starting price around $149.99/mo.
Choose Vytora Health if…
You want compounded or brand-name GLP-1 with named pharmacy partners, 50 states and a starting price around $150/mo.
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From $175/mo
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Mainstream telehealth GLP-1 access
From $146/mo
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Best overall value
From $135/mo
Get started →Helios Meds vs Vytora Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.