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Fierce Health vs Enhance MD

An in-depth comparison of two leading GLP-1 Providers

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6.9

Fierce Health

Best for Self-pay patients in the 30-state allowlist seeking compounded GLP-1 therapy with a microdose entry tier ($197/mo semaglutide microdose)Patients curious about low-dose 'microdose' GLP-1 protocols who want a published, verbatim service-area allowlistPatients comfortable with an unnamed 503A pharmacy partner and an unnamed clinical NP network in exchange for LegitScript certificationPatients who want a one-stop catalog spanning GLP-1, longevity supplements, and a companion meal plan
★★★★☆3.5

Starting at $/mo

Compounded semaglutide and compounded tirzepatide weight-loss programsMicrodose protocols for both semaglutide and tirzepatide ('low-dose for longevity/metabolic balance' framing)Monthly / 3-Month-in-Full / 6-Month-in-Full subscription cadencesGLP-1 companion meal plan and longevity catalog (NAD+, glutathione, methylene blue, ivermectin, mebendazole)
Visit Fierce Health →
8.6

Enhance MD

Best for lab-monitored compounded GLP-1 with mandatory video visit
★★★★☆4.3

Starting at $49/mo

CompoundedSemaglutideTirzepatideQuest Diagnostics Labs Included
Visit Enhance MD →

Side-by-Side Comparison

FeatureFierce HealthEnhance MD
Overall Score6.9/10✓8.6/10
Starting Price$/mo$49/mo
Editorial Rating3.5 ★ /5✓4.3 ★ /5
Features✓10 features6 features
States Available30✓39
Compounded—✓ Yes
Brand Name——
FSA/HSA Accepted——
FDA Warnings5 warnings✓None

Pros & Cons

Fierce Health

Pros

  • ✓30-state service allowlist enumerated verbatim in Terms of Service — buyer can verify eligibility upfront without intake
  • ✓LegitScript Certified with confirmed seal ID 24519532 (script reference in homepage HTML)
  • ✓Verbatim FDA-compounded disclaimer published on every product page ('Compounded medications are not reviewed by the FDA for safety or efficacy')
  • ✓Four GLP-1 programs (standard semaglutide / standard tirzepatide / microdose semaglutide / microdose tirzepatide) — broader compounded ladder than peers that only sell one or two SKUs
  • ✓Microdose tier at $197/mo is one of the lower entry points in the WLR compounded-semaglutide cluster
  • ✓Refund-on-unsupported-state policy is explicit ('if we can't ship to you, you will be refunded')
  • ✓Subscription cadences (Monthly / 3-Month / 6-Month) match category conventions

Cons

  • ✗No named 503A compounding pharmacy partner disclosed publicly — only the generic phrase 'prescriptions are fulfilled by partner pharmacies' appears on homepage, product pages, and About page
  • ✗Operating LLC name not disclosed anywhere on the site (homepage, About, Terms); only Idaho governing-law jurisdiction is published, suggesting Idaho-domiciled operator but no LLC name verifiable
  • ✗Tirzepatide Weight Loss Program ($497/mo) is showing 'sold out or unavailable' on all three subscription cadences at verification time — flagged as inventory/operational concern
  • ✗Clinical 'Licensed Nurse Practitioner' provider network not named (no clinical MSO or PA disclosed unlike Coby/BraveRx/AVARA which name Beluga Health)
  • ✗Heavy gray-market longevity catalog (ivermectin, ivermectin+mebendazole, methylene blue) coexists with GLP-1 catalog — unusual for a GLP-1-primary brand and raises a category-mix concern
  • ✗No PCAB pharmacy accreditation badge, no BBB profile, no NABP .Pharmacy badge visible — only LegitScript
  • ✗Tirzepatide weight-loss tier at $497/mo is at the high end of the WLR compounded-tirzepatide cluster
  • ✗Compounded semaglutide and compounded tirzepatide are not FDA-approved and have not been evaluated by FDA for safety or efficacy
  • ✗Underlying Shopify backend domain is 'fitness-carli.myshopify.com' suggesting an origin from an influencer-led 'Fitness Carli' brand rather than a clinical operator — flagged for editorial scrutiny

Enhance MD

Pros

  • ✓Baseline and ongoing metabolic lab panels (CMP, lipids, TSH, HbA1c) at Quest Diagnostics every 6 months — a rigor most compounded GLP-1 providers skip entirely
  • ✓Mandatory one-on-one video visit with a US-licensed MD or NP before the first prescription — not a pure-async questionnaire model
  • ✓Three pricing tiers including a combined semaglutide + tirzepatide Elite plan ($322/mo ongoing) — useful for patients plateaued on a single GLP-1
  • ✓LegitScript-certified 503A pharmacy network: Tru Meds Rx, Strive Pharmacy, Pharmacy Hub
  • ✓Aggressive first-month intro pricing: $49 on Core, $99 on Advanced, $189 on Elite
  • ✓Unlimited clinician messaging and dose-adjustment support included

Cons

  • ✗Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro option
  • ✗Not available in 10 states: Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, South Carolina, Tennessee, West Virginia
  • ✗Mandatory lab work adds 5–10 days to onboarding vs. async-only competitors
  • ✗No insurance accepted — cash pay, HSA/FSA eligible
  • ✗First-month intro pricing resets to full tier rate after 30 days — the $49/$99/$189 numbers are not the ongoing cost

Our Verdict

Winner: Enhance MDScore: 8.6/10

Enhance MD edges out Fierce Health with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. Fierce Health remains a solid alternative, especially if you're looking for Self-pay patients in the 30-state allowlist seeking compounded GLP-1 therapy with a microdose entry tier ($197/mo semaglutide microdose),Patients curious about low-dose 'microdose' GLP-1 protocols who want a published, verbatim service-area allowlist,Patients comfortable with an unnamed 503A pharmacy partner and an unnamed clinical NP network in exchange for LegitScript certification,Patients who want a one-stop catalog spanning GLP-1, longevity supplements, and a companion meal plan.

Get Started with Fierce Health →Get Started with Enhance MD →

Glossary references

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