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ElixaMD vs Enhance MD

An in-depth comparison of two leading GLP-1 Providers

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7.7

ElixaMD

Best for Shoppers wanting low-cost compounded semaglutide with free dietician and coaching included
★★★★☆3.9

Starting at $179/mo

CompoundedSemaglutideFree shippingHSA/FSA eligible
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8.6

Enhance MD

Best for lab-monitored compounded GLP-1 with mandatory video visit
★★★★☆4.3

Starting at $212/mo

CompoundedSemaglutideTirzepatideVideo Visit
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Side-by-Side Comparison

FeatureElixaMDEnhance MD
Overall Score7.7/10✓8.6/10
Starting Price✓$179/mo$212/mo
Editorial Rating3.9 ★ /5✓4.3 ★ /5
Features✓8 features6 features
States Available0✓39
Compounded✓ Yes✓ Yes
Brand Name——
FSA/HSA Accepted✓ Yes—
FDA WarningsNoneNone

Pros & Cons

ElixaMD

What we like

  • Compounded semaglutide from $179 first month with free shipping, no membership, no contract, and no insurance required
  • Genuinely all-inclusive: 1:1 physician guidance, free dietician visits and care coaching, 24/7 support, and an all-in-one patient portal
  • Names its compounding pharmacies (RedRock Pharmacy, Beaker Pharmacy) — more transparent than most compounded sellers
  • HSA/FSA eligible; full legal suite (Terms, Privacy, Privacy Practices, Refund, Medical Consent, California Bill of Rights)

Watch-outs

  • $179 is a first-month/intro price — ongoing monthly cost is higher (tiers to ~$249-$299)
  • Compounded semaglutide is not FDA-approved (the site discloses this) — not brand Wegovy or Ozempic
  • Appears to offer compounded semaglutide only — tirzepatide is not advertised
  • Displays a generic LegitScript Certified badge but no verifiable seal/listing; state-availability list not published

Enhance MD

What we like

  • Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
  • Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
  • Three tiers, including a combined semaglutide + tirzepatide Elite plan ($322/mo) for patients plateaued on one GLP-1
  • Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
  • Low first-month intro pricing: $49 Core, $99 Advanced, $189 Elite
  • Unlimited clinician messaging and dose-adjustment support included

Watch-outs

  • Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
  • Not available in 10 states: AL, AR, GA, HI, LA, MS, MO, SC, TN, WV
  • Mandatory lab work adds 5–10 days to onboarding vs async-only competitors
  • No insurance accepted — cash pay, HSA/FSA eligible
  • Intro pricing resets to full tier rate after 30 days — the $49/$99/$189 figures aren't ongoing cost

Our Verdict

Winner: Enhance MDScore: 8.6/10

Enhance MD edges out ElixaMD with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. ElixaMD remains a solid alternative, especially if you're looking for Shoppers wanting low-cost compounded semaglutide with free dietician and coaching included.

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.