Dr. Gillis' Wellness Center vs Enhance MD
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Dr. Gillis' Wellness Center
Best for Patients wanting sublingual ODT GLP-1 tablets or a needle-free weight-loss optionStarting at $149/mo
Enhance MD
Best for lab-monitored compounded GLP-1 with mandatory video visitStarting at $49/mo
Side-by-Side Comparison
| Feature | Dr. Gillis' Wellness Center | Enhance MD |
|---|---|---|
| Overall Score | 7.3/10 | ✓8.6/10 |
| Starting Price | $149/mo | ✓$49/mo |
| Editorial Rating | 3.7 ★ /5 | ✓4.3 ★ /5 |
| Features | ✓8 features | 6 features |
| States Available | 0 | ✓39 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
Dr. Gillis' Wellness Center
Pros
- ✓Sublingual ODT tablets offered as needle-free alternative
- ✓Broad GLP-1 menu: semaglutide, tirzepatide, and retatrutide
- ✓Transparent pricing: $150 starting dose, plans from $149/mo
- ✓Led by board-certified physician/surgeon with 25+ years experience
- ✓No contracts; flexible weekly, bi-weekly, or monthly cadence
Cons
- ✗Specific dose-tier pricing beyond starting plan not detailed
- ✗Compounded vs brand not explicitly stated for all meds
- ✗Smaller clinic vs national telehealth brands
- ✗State licensing list not published
Enhance MD
Pros
- ✓Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
- ✓Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
- ✓Three tiers, including a combined semaglutide + tirzepatide Elite plan ($322/mo) for patients plateaued on one GLP-1
- ✓Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
- ✓Low first-month intro pricing: $49 Core, $99 Advanced, $189 Elite
- ✓Unlimited clinician messaging and dose-adjustment support included
Cons
- ✗Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- ✗Not available in 10 states: AL, AR, GA, HI, LA, MS, MO, SC, TN, WV
- ✗Mandatory lab work adds 5–10 days to onboarding vs async-only competitors
- ✗No insurance accepted — cash pay, HSA/FSA eligible
- ✗Intro pricing resets to full tier rate after 30 days — the $49/$99/$189 figures aren't ongoing cost
Our Verdict
Enhance MD edges out Dr. Gillis' Wellness Center with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. Dr. Gillis' Wellness Center remains a solid alternative, especially if you're looking for Patients wanting sublingual ODT GLP-1 tablets or a needle-free weight-loss option.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring Dr. Gillis' Wellness Center and Enhance MD head-to-heads in the same category.
- Dr. Gillis' Wellness Center vs CoreAge Rx
- Dr. Gillis' Wellness Center vs TrimRx
- Dr. Gillis' Wellness Center vs Amazon One Medical
- Enhance MD vs NovoCare Pharmacy
- Enhance MD vs Vytora Health
- Enhance MD vs Noom Med
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.