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Coby Health vs Enhance MD

An in-depth comparison of two leading GLP-1 Providers

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7.3

Coby Health

Best for Budget-conscious patients comfortable with no-membership cash-pay compounded GLP-1 who don't require pharmacy-partner transparency
★★★3.7

Starting at $159/mo

Compounded Semaglutide (from $99/mo 6-mo bundle)Compounded Tirzepatide (from $179/mo 6-mo bundle)LegitScript Certified (seal 38387067)Beluga Health P.A. clinical network
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8.6

Enhance MD

Best for lab-monitored compounded GLP-1 with mandatory video visit
★★★★4.3

Starting at $49/mo

CompoundedSemaglutideTirzepatideQuest Diagnostics Labs Included
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Side-by-Side Comparison

FeatureCoby HealthEnhance MD
Overall Score7.3/108.6/10
Starting Price$159/mo$49/mo
Editorial Rating3.7 ★ /54.3 ★ /5
Features8 features6 features
States Available4639
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

Pros & Cons

Coby Health

Pros

  • LegitScript Certified (seal 38387067)
  • No membership fee
  • Aggressive 6-month bundle pricing
  • Beluga Health P.A. clinical network — board-certified, 50-state licensure
  • Trustpilot 4.9/5 (~83 reviews)
  • No FDA Warning Letters as of 2026-05-25

Cons

  • Does NOT publicly name compounding pharmacy partner(s) — transparency gap vs Belle/Joi+Blokes
  • Compounded medications are not FDA-approved
  • Tirzepatide pricing escalates steeply ($439/mo at 15mg monthly)
  • $50 non-refundable cancellation fee
  • No oral GLP-1 options
  • Founder/CEO not publicly disclosed
  • Not available in AR, LA, MS, NM

Enhance MD

Pros

  • Baseline and ongoing metabolic lab panels (CMP, lipids, TSH, HbA1c) at Quest Diagnostics every 6 months — a rigor most compounded GLP-1 providers skip entirely
  • Mandatory one-on-one video visit with a US-licensed MD or NP before the first prescription — not a pure-async questionnaire model
  • Three pricing tiers including a combined semaglutide + tirzepatide Elite plan ($322/mo ongoing) — useful for patients plateaued on a single GLP-1
  • LegitScript-certified 503A pharmacy network: Tru Meds Rx, Strive Pharmacy, Pharmacy Hub
  • Aggressive first-month intro pricing: $49 on Core, $99 on Advanced, $189 on Elite
  • Unlimited clinician messaging and dose-adjustment support included

Cons

  • Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro option
  • Not available in 10 states: Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, South Carolina, Tennessee, West Virginia
  • Mandatory lab work adds 5–10 days to onboarding vs. async-only competitors
  • No insurance accepted — cash pay, HSA/FSA eligible
  • First-month intro pricing resets to full tier rate after 30 days — the $49/$99/$189 numbers are not the ongoing cost

Our Verdict

Winner: Enhance MDScore: 8.6/10

Enhance MD edges out Coby Health with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. Coby Health remains a solid alternative, especially if you're looking for Budget-conscious patients comfortable with no-membership cash-pay compounded GLP-1 who don't require pharmacy-partner transparency.

Glossary references

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.