Brightmeds vs Enhance MD
In our scoring, Enhance MD edges ahead overall (8.2 vs 7.4 out of 10), and Brightmeds costs less for compounded semaglutide (about $276 a year less).
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Key differences
- Price
- Brightmeds $189/mo vs Enhance MD $212/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $276 a year less with Brightmeds)
- Coverage
- Brightmeds 47 states; Enhance MD 39 states (only Brightmeds: Georgia, Hawaii, Louisiana and 5 more)
- Included
- Brightmeds: medication, clinician visits, shipping, labs; Enhance MD: medication, clinician visits, labs
Brightmeds
Affiliate partnerBest for compounded or brand GLP-1 bundled with TRT and peptides for men
semaglutide
$189
Our score 7.4/10
Enhance MD
Affiliate partnerBest for lab-monitored compounded GLP-1 with mandatory video visit
semaglutide
$212
$112 first month
Our score 8.2/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Brightmeds
Enhance MD
Price
Semaglutide / month
Better on this row: $189/mo
$212/mo
$112 first month
Semaglutide / year (modeled)
Better on this row: $2,268
$2,544
Tirzepatide / month
$289/mo
Better on this row: $169/mo
Tirzepatide / year (modeled)
$3,468
Better on this row: $2,028
Coverage
State availability
47 states
39 states
Included in the price
Medication, clinician visits, shipping, labs
Medication, clinician visits, labs
Terms & safety
Price shown
Plan quoted after intake; a price is published
Before intake
Lab work
Not disclosed
Required
Video visit
Not disclosed
Required
Cancel anytime
Not disclosed
Yes
Minimum commitment
Not disclosed
None
Refunds
Conditional 6-mo money-back guarantee
Not disclosed
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
Show where they differ by stateHide state lists
Only Brightmeds (8 states)
- Georgia
- Hawaii
- Louisiana
- Missouri
- North Dakota
- South Carolina
- Tennessee
- West Virginia
Every dose and plan: Brightmeds · Enhance MD
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Brightmeds if…
- About $276 a year less than Enhance MD for compounded semaglutide at standing prices
- Serves 8 states that Enhance MD doesn't
- One login covers GLP-1, TRT, peptides, and longevity — convenient for men exploring weight loss and hormones
What to weigh up
- Pricing isn't itemized on the main pages — you must click through to landers or the application flow
- Brand-name Zepbound carries a separate $100 doctor consult fee on top of drug cost
Choose Enhance MD if…
- Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
- Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
- Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
What to weigh up
- About $276 a year more than Brightmeds for compounded semaglutide
- Not available in 8 states that Brightmeds serves
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Brightmeds
7.4/10
Enhance MD
8.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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From $299/mo
Get started →SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo + membership
Get started →Brightmeds vs Enhance MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.