Aquivia Health vs Enhance MD
An in-depth comparison of two leading GLP-1 Providers
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Aquivia Health
Best for Self-pay patients who want a clinician-reviewed (not algorithmic) compounded-GLP-1 pathway at the low end of the WLR compounded cluster ($149/mo semaglutide, $179/mo tirzepatide) AND want the option to upgrade to branded Ozempic/Zepbound at the same operator. Buyers who value a named clinical MSO partner (Open Loop Healthcare Partners, PC) and a co-founder team that publicly discloses credentials (MD + PharmD + operations executive). NOT ideal for buyers who require an upfront state-availability disclosure (Aquivia does not publish a state allowlist), buyers who require LegitScript/PCAB/BBB badges in the footer as a precondition (none visible in this verification pass), or buyers in coming-soon program categories (Performance Longevity, Dysautonomia/POTS are waitlist-only).Starting at $149/mo
Enhance MD
Best for lab-monitored compounded GLP-1 with mandatory video visitStarting at $49/mo
Side-by-Side Comparison
| Feature | Aquivia Health | Enhance MD |
|---|---|---|
| Overall Score | 6.9/10 | ✓8.6/10 |
| Starting Price | $149/mo | ✓$49/mo |
| Editorial Rating | 3.5 ★ /5 | ✓4.3 ★ /5 |
| Features | ✓10 features | 6 features |
| States Available | 0 | ✓39 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | 4 warnings | ✓None |
Pros & Cons
Aquivia Health
Pros
- ✓Named clinical partner disclosed verbatim in site footer: 'Clinical care services provided by our partner clinicians at Open Loop Healthcare Partners, PC: openloophealth.com' — same MSO network used by several other DTC GLP-1 brands, which is a reused-and-verified trust signal
- ✓Named leadership team with credentials disclosed: Steven Bishop MD (CMO, Internal Medicine), Phillip Gray PharmD (Chief Pharmacist, 503A/USP background), Tom Foster (President)
- ✓Itemized pricing displayed publicly on /pricing and /programs/glp-1-weight-loss — Compounded Semaglutide $149/mo, Compounded Tirzepatide $179/mo, Ozempic $1,299/shipment, Zepbound $1,399/shipment
- ✓Both compounded AND branded GLP-1 options offered side-by-side, which is unusual — most DTC compounded providers do not also carry branded Ozempic/Zepbound
- ✓Self-pay model with no insurance required and no separate consultation fee (consult bundled into the monthly product price)
- ✓Multi-month prepay discounts disclosed publicly ('save $910 vs billed every 4 weeks' on 52-week semaglutide and tirzepatide tiers)
- ✓Explicit no-guarantee disclaimer ('Completing the check does not guarantee a prescription') is a positive clinical-safety signal vs platforms that imply guaranteed prescriptions
- ✓Multi-program platform with metabolic, longevity, and dysautonomia pathways (latter two waitlist-only) suggests a broader clinical scope than single-vertical compounded shops
Cons
- ✗No public state-availability allowlist — marketing copy says 'Nationwide distribution *where allowed by state law' but the FAQ acknowledges 'Not all therapies are available in every state' without disclosing which states are excluded; buyer must complete the eligibility intake to learn whether their state qualifies
- ✗No named 503A compounding pharmacy partner disclosed publicly — the homepage and pricing page reference '503A Pharmacy Standard' and 'licensed 503A compounding pharmacies' but do not name a specific pharmacy operator, limiting independent licensure verification
- ✗No LegitScript, PCAB, or BBB trust-signal badges visible on the homepage footer in this verification pass — a meaningful omission for a DTC compounded-GLP-1 platform launched 2026-Q1 (site Schema.org datePublished 2026-04-21)
- ✗Brand confusion risk: schema.org Organization name on the homepage is 'CatalystMD' (with a CatalystMD logo file referenced) while the customer-facing brand is 'Aquivia Health' — the parent/operating-entity relationship is not disclosed in the public footer or About page in this verification pass
- ✗Compounded semaglutide and tirzepatide are not FDA-approved and have not undergone FDA premarket review for safety, efficacy, or manufacturing quality
- ✗Site is recently launched (Schema.org datePublished 2026-04-21, dateModified 2026-05-24) with no Trustpilot, BBB, or third-party-reviews profile yet that could be independently verified
- ✗Two of the three advertised programs (Performance Longevity, Dysautonomia/POTS) are waitlist-only — only the GLP-1 Weight Loss / Metabolic Health pathway is currently 'Available Now'
Enhance MD
Pros
- ✓Baseline and ongoing metabolic lab panels (CMP, lipids, TSH, HbA1c) at Quest Diagnostics every 6 months — a rigor most compounded GLP-1 providers skip entirely
- ✓Mandatory one-on-one video visit with a US-licensed MD or NP before the first prescription — not a pure-async questionnaire model
- ✓Three pricing tiers including a combined semaglutide + tirzepatide Elite plan ($322/mo ongoing) — useful for patients plateaued on a single GLP-1
- ✓LegitScript-certified 503A pharmacy network: Tru Meds Rx, Strive Pharmacy, Pharmacy Hub
- ✓Aggressive first-month intro pricing: $49 on Core, $99 on Advanced, $189 on Elite
- ✓Unlimited clinician messaging and dose-adjustment support included
Cons
- ✗Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro option
- ✗Not available in 10 states: Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, South Carolina, Tennessee, West Virginia
- ✗Mandatory lab work adds 5–10 days to onboarding vs. async-only competitors
- ✗No insurance accepted — cash pay, HSA/FSA eligible
- ✗First-month intro pricing resets to full tier rate after 30 days — the $49/$99/$189 numbers are not the ongoing cost
Our Verdict
Enhance MD edges out Aquivia Health with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. Aquivia Health remains a solid alternative, especially if you're looking for Self-pay patients who want a clinician-reviewed (not algorithmic) compounded-GLP-1 pathway at the low end of the WLR compounded cluster ($149/mo semaglutide, $179/mo tirzepatide) AND want the option to upgrade to branded Ozempic/Zepbound at the same operator. Buyers who value a named clinical MSO partner (Open Loop Healthcare Partners, PC) and a co-founder team that publicly discloses credentials (MD + PharmD + operations executive). NOT ideal for buyers who require an upfront state-availability disclosure (Aquivia does not publish a state allowlist), buyers who require LegitScript/PCAB/BBB badges in the footer as a precondition (none visible in this verification pass), or buyers in coming-soon program categories (Performance Longevity, Dysautonomia/POTS are waitlist-only)..
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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