Alloy vs Calibrate Health
An in-depth comparison of two leading GLP-1 Providers
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Alloy
Best for women in menopause/perimenopause who want a Menopause Society-certified clinician AND the broadest brand+compounded GLP-1 formulary in our directoryStarting at $80/mo
Calibrate Health
Best for patients with insurance coverage who want a year-long coaching-wrap around branded Wegovy / Zepbound / FoundayoStarting at $25/mo
Side-by-Side Comparison
| Feature | Alloy | Calibrate Health |
|---|---|---|
| Overall Score | 7.4/10 | ✓7.9/10 |
| Starting Price | $80/mo | ✓$25/mo |
| Editorial Rating | 3.7 ★ /5 | ✓4 ★ /5 |
| Features | 8 features | ✓9 features |
| States Available | 0 | ✓50 |
| Compounded | ✓ Yes | — |
| Brand Name | ✓ Yes | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
Alloy
Pros
- ✓Broadest GLP-1 formulary in our catalog: brand Wegovy + brand Zepbound + oral Wegovy + compounded semaglutide + compounded tirzepatide + compounded liraglutide
- ✓All consulting doctors are certified by The Menopause Society — only ~1,000 such certified practitioners exist among ~20,000 OB-GYNs in the US
- ✓Brand-name Wegovy starting at $199/mo and compounded liraglutide starting at $80/mo cover both ends of the price/access spectrum
- ✓STARTGLP1 promo code knocks $50 off the first month per the public site
Cons
- ✗Not available in Louisiana or Mississippi (verified) — readers in those two states should be routed elsewhere
- ✗Initial consultation is $49 and is separate from medication cost — readers should know there's a non-refundable upfront fee
- ✗Menopause-specialty framing — best fit for women in menopause/perimenopause, not the right product for men or younger women whose primary need is weight loss
Calibrate Health
Pros
- ✓Year-long structured program with 1:1 video coaching, registered-dietitian support, and curriculum-based behavior-change content — deeper clinical wrap than transactional telehealth providers
- ✓$199/month program fee is competitive for a coaching-included GLP-1 program; medication co-pay drops to ~$25/month with insurance + manufacturer savings card
- ✓Branded GLP-1s only (Wegovy, Ozempic, Zepbound, Foundayo) — no compounded products, no FDA gray-zone risk
- ✓Insurance navigation team works with patients to maximize coverage; reportedly accepts most major commercial plans
- ✓Money-back guarantee tied to weight-loss outcomes (10% reduction over the program year) signals confidence in the program model
- ✓Published 3-year outcomes data ('19% mean weight loss' per Calibrate's pricing page) is more transparent than most weight-loss programs
Cons
- ✗12-month commitment with quarterly billing ($597 every 3 months) is a much higher financial lock-in than month-to-month telehealth providers — not refundable mid-program
- ✗Medication cost is on top of the $199/month program fee — cash-pay patients without insurance face full manufacturer pricing for Wegovy/Zepbound on top of the program fee, which makes the all-in cost meaningfully higher than compounded-GLP-1 telehealth providers
- ✗Insurance navigation depends on actually having coverage for branded GLP-1s for weight loss — most commercial plans still don't cover Wegovy/Zepbound for obesity without medical necessity
- ✗Program is structured around branded GLP-1s; if your insurance denies coverage and you need a more affordable channel, Calibrate is meaningfully more expensive than compounded telehealth alternatives
- ✗Distinct from 'Oxford's Medical Weight Loss (The Calibrate Clinic)' already in our directory — don't confuse the two when shopping
Our Verdict
Calibrate Health edges out Alloy with a higher overall score of 7.9/10 and is particularly strong for patients with insurance coverage who want a year-long coaching-wrap around branded Wegovy / Zepbound / Foundayo. Alloy remains a solid alternative, especially if you're looking for women in menopause/perimenopause who want a Menopause Society-certified clinician AND the broadest brand+compounded GLP-1 formulary in our directory.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.