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Actin vs Tyde Wellness

An in-depth comparison of two leading GLP-1 Providers

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7.0

Actin

Best for affordable compounded semaglutide with B12 enhancement
★★★3.5

Starting at $133/mo

Compounded SemaglutideB12 Enhanced
Visit Actin
8.3

Tyde Wellness

Best for Cash-pay patients wanting transparent compounded-GLP-1 pricing with named, LegitScript-certified pharmacy fulfillment and the option to bundle menopause/HRT, hair loss, or longevity peptides through a single 50-state provider.
★★★★4.2

Starting at $119/mo

Compounded Semaglutide ($149/mo+)Compounded Tirzepatide ($249/mo+)Low-Dose Naltrexone ($119/mo+)All 50 States
Visit Tyde Wellness

Side-by-Side Comparison

FeatureActinTyde Wellness
Overall Score7.0/108.3/10
Starting Price$133/mo$119/mo
Editorial Rating3.5 ★ /54.2 ★ /5
Features2 features10 features
States Available050
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

Pros & Cons

Actin

Pros

  • Semaglutide + B12 combination for added energy support
  • Transparent pricing — exact cost shown upfront with no hidden fees
  • Competitive starting price from $133

Cons

  • Semaglutide only — no tirzepatide or liraglutide
  • No visible LegitScript or PCAB accreditation
  • State availability not disclosed
  • Broader platform (hormones, sexual wellness, hair health)

Tyde Wellness

Pros

  • All 50 states served (verbatim list disclosed on /states-we-serve)
  • Pricing publicly transparent: semaglutide from $149/mo, tirzepatide from $249/mo
  • LegitScript-certified with badge linking to verification
  • Five named LegitScript-certified 503A pharmacy partners disclosed with verbatim addresses (Belmar CO, Casa TX, Olympia FL, Red Rock UT, Beaker TX)
  • Free consultation; cancel-anytime subscription with no long-term commitment
  • Microdose and full-strength options for both GLP-1s
  • Multi-vertical platform — single account covers weight loss, HRT, hair, longevity peptides

Cons

  • Compounded semaglutide and tirzepatide are NOT FDA-approved finished drug products
  • Brand-name GLP-1s (Wegovy, Zepbound, Mounjaro, Ozempic) not offered
  • Tirzepatide pricing higher than several competitors offering $200-$249/mo bundles
  • Corporate address and named medical director not publicly disclosed
  • No NABP .pharmacy seal visible

Our Verdict

Winner: Tyde WellnessScore: 8.3/10

Tyde Wellness edges out Actin with a higher overall score of 8.3/10 and is particularly strong for Cash-pay patients wanting transparent compounded-GLP-1 pricing with named, LegitScript-certified pharmacy fulfillment and the option to bundle menopause/HRT, hair loss, or longevity peptides through a single 50-state provider.. Actin remains a solid alternative, especially if you're looking for affordable compounded semaglutide with B12 enhancement.

Glossary references

Key terms in this article, linked to their canonical definitions.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.