Actin vs RxPros
An in-depth comparison of two leading GLP-1 Providers
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Actin
Best for affordable compounded semaglutide with B12 enhancementStarting at $133/mo
RxPros
Best for price-sensitive patients comfortable with annual prepayment to lock in the lowest compounded GLP-1 monthly rate in the marketStarting at $99.99/mo
Side-by-Side Comparison
| Feature | Actin | RxPros |
|---|---|---|
| Overall Score | 7.0/10 | ✓7.6/10 |
| Starting Price | $133/mo | ✓$99.99/mo |
| Editorial Rating | 3.5 ★ /5 | ✓3.8 ★ /5 |
| Features | 2 features | ✓6 features |
| States Available | 0 | 0 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
Actin
Pros
- ✓Semaglutide + B12 combination for added energy support
- ✓Transparent pricing — exact cost shown upfront with no hidden fees
- ✓Competitive starting price from $133
Cons
- ✗Semaglutide only — no tirzepatide or liraglutide
- ✗No visible LegitScript or PCAB accreditation
- ✗State availability not disclosed
- ✗Broader platform (hormones, sexual wellness, hair health)
RxPros
Pros
- ✓$99.99/month compounded semaglutide is in the cheapest decile of the US compounded telehealth market — competitive with the lowest-priced peer platforms
- ✓$144.97/month compounded tirzepatide is at the lower end of the tirzepatide compounded range
- ✓LegitScript Certified seal displayed
- ✓Named legal entity (RxPros LLC) with physical Wyoming address — better entity transparency than peer platforms that show only a brand name
- ✓Overnight cold-packed shipping disclosed (important for GLP-1 cold-chain integrity)
- ✓FDA-regulated 503A pharmacies referenced
- ✓Add-on Zofran (anti-nausea) and B12 available — useful for patients managing GI side effects during titration
Cons
- ✗Headline pricing requires annual prepayment OR is presented as 'introductory' — month-to-month and quarterly pricing tiers not clearly disclosed on the home page
- ✗Per-state availability NOT enumerated publicly — verify your state ships before committing
- ✗Specific 503A pharmacy partner names NOT publicly disclosed — material YMYL transparency gap
- ✗State of incorporation NOT explicitly stated (Wyoming address suggests WY incorporation but not confirmed)
- ✗Lab work NOT included as standard
- ✗LegitScript certification number NOT publicly displayed (seal-only)
Our Verdict
RxPros edges out Actin with a higher overall score of 7.6/10 and is particularly strong for price-sensitive patients comfortable with annual prepayment to lock in the lowest compounded GLP-1 monthly rate in the market. Actin remains a solid alternative, especially if you're looking for affordable compounded semaglutide with B12 enhancement.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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