Actin vs Ondra Health
An in-depth comparison of two leading GLP-1 Providers
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Actin
Best for affordable compounded semaglutide with B12 enhancementStarting at $133/mo
Ondra Health
Best for Cost-sensitive patients who want the lowest compounded-GLP-1 monthly cost and are willing to commit quarterly.Starting at $93/mo
Side-by-Side Comparison
| Feature | Actin | Ondra Health |
|---|---|---|
| Overall Score | 7.0/10 | ✓7.7/10 |
| Starting Price | $133/mo | ✓$93/mo |
| Editorial Rating | 3.5 ★ /5 | ✓3.9 ★ /5 |
| Features | 2 features | ✓8 features |
| States Available | 0 | ✓51 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
Actin
Pros
- ✓Semaglutide + B12 combination for added energy support
- ✓Transparent pricing — exact cost shown upfront with no hidden fees
- ✓Competitive starting price from $133
Cons
- ✗Semaglutide only — no tirzepatide or liraglutide
- ✗No visible LegitScript or PCAB accreditation
- ✗State availability not disclosed
- ✗Broader platform (hormones, sexual wellness, hair health)
Ondra Health
Pros
- ✓Aggressive quarterly pricing — $93/mo effective for semaglutide is among the lowest in the segment
- ✓Named provider physicians (5 listed) — more transparency than typical compounded-GLP-1 platform
- ✓Five named 503A pharmacy partners disclosed
- ✓LegitScript seal + HIPAA claim displayed
- ✓Licensed in all 50 states
Cons
- ✗No brand-name GLP-1 option (Wegovy/Zepbound/Mounjaro not offered)
- ✗Corporate physical address not disclosed
- ✗Hallandale pharmacy excluded in 9 states (CA, KS, AR, MI, MN, AL, HI, MS, MA) — fulfillment routing may vary
- ✗No medical director named
- ✗LegitScript certification number not displayed on visible pages
Our Verdict
Ondra Health edges out Actin with a higher overall score of 7.7/10 and is particularly strong for Cost-sensitive patients who want the lowest compounded-GLP-1 monthly cost and are willing to commit quarterly.. Actin remains a solid alternative, especially if you're looking for affordable compounded semaglutide with B12 enhancement.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.