24hrDOC vs Sesame Care
An in-depth comparison of two leading GLP-1 Providers
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24hrDOC
Best for Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatideStarting at $149/mo
Sesame Care
Best for Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compoundingStarting at $25/mo
Side-by-Side Comparison
| Feature | 24hrDOC | Sesame Care |
|---|---|---|
| Overall Score | 7.1/10 | ✓7.5/10 |
| Starting Price | $149/mo | ✓$25/mo |
| Editorial Rating | 3.6 ★ /5 | ✓3.8 ★ /5 |
| Features | 8 features | 8 features |
| States Available | 0 | 0 |
| Compounded | ✓ Yes | — |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
24hrDOC
Pros
- ✓Low compounded semaglutide price, around 149 per month
- ✓Fast model: 10-minute assessment, Rx within 45 minutes
- ✓Injectable and oral semaglutide plus tirzepatide options
- ✓24/7 availability with unlimited provider messaging
Cons
- ✗Compounded only, not FDA-approved branded GLP-1s
- ✗Self-pay only, no insurance accepted
- ✗States served not disclosed on the site
- ✗Fast-prescribing model offers less in-depth clinical workup
Sesame Care
Pros
- ✓Marketplace transparency — pick a named provider with a displayed price before booking, unlike most opaque telehealth intake
- ✓BBB-accredited and LegitScript-verified
- ✓LillyDirect partnership unlocks Zepbound vial and KwikPen cash pricing matching Lilly's lowest direct rates ($299 at lowest dose)
- ✓Wegovy self-pay promo ($199/mo for first two months, lowest dose, new self-pay) — among the lowest brand-Wegovy cash prices, through 2026-06-30
- ✓Honest subscription scope — clinical care only, medication billed separately
- ✓Stocks both Wegovy pill ($149/mo low doses) and Foundayo orforglipron alongside injectables
- ✓Lab work included in subscription for 41 states (excludes AZ/HI/ND/NJ/NY/OK/RI/SD/WY)
- ✓Insurance route ($25/mo possible) is viable — providers assist with prior authorization
Cons
- ✗Marketplace model means clinician credentials and quality vary provider to provider
- ✗Statewide availability can't be listed — it depends on which marketplace providers are licensed in your state
- ✗No in-house pharmacy — fulfillment splits across LillyDirect, NovoCare, and your retail pharmacy
- ✗Restrictive refunds — full refund only if you cancel 3+ hours before the first visit; no refund once the visit occurs
- ✗Subscription commitment required — no genuine pay-per-visit option for weight loss
- ✗Wegovy $199/mo promo applies only to new self-pay patients at the lowest dose; $349/mo after month 2
- ✗Wegovy pill high doses ($299/mo for 9mg/25mg) cost about 2x the low-dose price as you titrate up
- ✗Zepbound KwikPen high doses ($699/mo for 10–15mg) approach Lilly's list price
Our Verdict
Sesame Care edges out 24hrDOC with a higher overall score of 7.5/10 and is particularly strong for Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compounding. 24hrDOC remains a solid alternative, especially if you're looking for Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.