24hrDOC vs Knownwell
An in-depth comparison of two leading GLP-1 Providers
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24hrDOC
Best for Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatideStarting at $149/mo
Knownwell
Best for Patients wanting branded GLP-1s with obesity-medicine oversight and insurance optionsStarting at $349/mo
Side-by-Side Comparison
| Feature | 24hrDOC | Knownwell |
|---|---|---|
| Overall Score | 7.1/10 | ✓7.8/10 |
| Starting Price | ✓$149/mo | $349/mo |
| Editorial Rating | 3.6 ★ /5 | ✓3.9 ★ /5 |
| Features | 8 features | 8 features |
| States Available | 0 | 0 |
| Compounded | ✓ Yes | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
24hrDOC
Pros
- ✓Low compounded semaglutide price, around 149 per month
- ✓Fast model: 10-minute assessment, Rx within 45 minutes
- ✓Injectable and oral semaglutide plus tirzepatide options
- ✓24/7 availability with unlimited provider messaging
Cons
- ✗Compounded only, not FDA-approved branded GLP-1s
- ✗Self-pay only, no insurance accepted
- ✗States served not disclosed on the site
- ✗Fast-prescribing model offers less in-depth clinical workup
Knownwell
Pros
- ✓Co-founded by obesity-medicine specialist Dr. Angela Fitch
- ✓Branded FDA-approved GLP-1s (Wegovy, Zepbound, Ozempic, Saxenda)
- ✓Official LillyDirect provider and Novo Wegovy-pill telehealth partner
- ✓Accepts insurance, copays as low as $25 for covered patients
- ✓Weight-inclusive care with dietitians and health coaches
- ✓Both virtual (50 states) and in-person clinic options
Cons
- ✗Specific self-pay monthly medication prices not transparently posted
- ✗In-person clinics limited to four metro areas
- ✗Branded-only focus can mean higher cost than compounded routes
Our Verdict
Knownwell edges out 24hrDOC with a higher overall score of 7.8/10 and is particularly strong for Patients wanting branded GLP-1s with obesity-medicine oversight and insurance options. 24hrDOC remains a solid alternative, especially if you're looking for Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.