Is 24hrDOC or Blue Sky MD cheaper?

24hrDOC is cheaper. Its lowest ongoing monthly cash price is $149/mo, compared with $160/mo for Blue Sky MD. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.

Which is better overall, 24hrDOC or Blue Sky MD?

24hrDOC scores higher overall at 7.1/10 versus 6.6/10, and is particularly strong for Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide. That said, Blue Sky MD is a better fit if you want LegitScript-certified, NC-based; compounded sema $40/wk or tirz $60/wk; physician-led + 1-on-1 coaching.

Does 24hrDOC or Blue Sky MD cover more states?

Blue Sky MD lists availability in 1 state, while 24hrDOC's state list is not publicly listed.

Is 24hrDOC or Blue Sky MD an affiliate partner of Weight Loss Rankings?

Neither 24hrDOC nor Blue Sky MD is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.

Which is cheaper for Semaglutide, 24hrDOC or Blue Sky MD?

For Semaglutide, 24hrDOC is cheaper at $149/mo versus $160/mo at Blue Sky MD.

Always verify pricing and state availability on the provider's website before signing up.How our reviews work →

24hrDOC vs Blue Sky MD

Name: 24hrDOC
Brand: 24hrDOC
Price: 149 USD
Availability: InStock

An in-depth comparison of two leading GLP-1 Providers

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24hrDOC

7.1

★★★★☆3.6

Best for: Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide

Visit 24hrDOC →

Blue Sky MD

6.6

★★★☆☆3.3

Best for: LegitScript-certified, NC-based; compounded sema $40/wk or tirz $60/wk; physician-led + 1-on-1 coaching

Visit Blue Sky MD →

24hrDOC and Blue Sky MD are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 24hrDOC starts lower at $149/mo versus $160/mo, and 24hrDOC edges ahead overall (7.1 vs 6.6 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

24hrDOC

0.25-2 mg titrated, once weeklyCompounded

$149/mo

semaglutide

Oral semaglutide tabletsCompounded

$309/mo

semaglutide

Blue Sky MD

Starting doseCompounded

$160/mo

semaglutide

Verbatim: 'Semaglutide - $40/week in-office' and 'as low as $40/week'. Monthly estimate = $40 × 4 weeks = $160. Compounded formulation; dispensed in-office or shipped to home.

Starting doseCompounded

$240/mo

tirzepatide

Verbatim: 'Tirzepatide - $60/week in-office'. Monthly estimate = $60 × 4 weeks = $240. Compounded formulation; dispensed in-office or shipped to home.

What’s included

24hrDOC

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Blue Sky MD

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Included

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

24hrDOC

7.1/10

Overall

Blue Sky MD

6.6/10

Value25%

7.5

6.5

Effectiveness25%

7.0

User Experience15%

7.0

6.0

Trust & Safety15%

6.5

7.5

Accessibility10%

7.0

4.0

Support10%

7.0

7.5

Features & Coverage

Feature	24hrDOC	Blue Sky MD
Starting Price	✓$149/mo	$160/mo
Features	8 features	8 features
States Available	Not disclosed	1
Compounded	✓ Yes	✓ Yes
Brand Name	—	—
FSA/HSA Accepted	—	—
FDA Warnings	None	None

About 24hrDOC

24hrDOC is a fast cash-pay telehealth service that prescribes compounded GLP-1 medications for weight loss, including once-weekly semaglutide injections, oral semaglutide tablets, and tirzepatide. Compounded semaglutide runs about 149 dollars per month (from 249), with a 100 dollar first-order discount and doses titrated from 0.25 mg to 2 mg. The model emphasizes speed: a roughly 10-minute assessment, prescriptions within about 45 minutes, unlimited messaging, and discreet shipping from licensed pharmacies. Self-pay only, no insurance, operating 24/7. States served are not listed online.

Read our full 24hrDOC review →

About Blue Sky MD

Blue Sky MD is a LegitScript-certified medical weight-loss practice founded in 2008 with seven North Carolina clinics and telehealth visits available. The program offers compounded semaglutide starting at $40/week and compounded tirzepatide starting at $60/week, dispensed directly to patients’ homes within 3–5 business days. Physician-supervised care includes 1-on-1 wellness coaching, a nutrition tracking app, hormone analysis, and personalized weight-loss plans. Medication access requires enrollment in their full medical weight-loss program.

Read our full Blue Sky MD review →

Pros & Cons

24hrDOC

What we like

Low compounded semaglutide price, around 149 per month
Fast model: 10-minute assessment, Rx within 45 minutes
Injectable and oral semaglutide plus tirzepatide options
24/7 availability with unlimited provider messaging

Watch-outs

Compounded only, not FDA-approved branded GLP-1s
Self-pay only, no insurance accepted
States served not disclosed on the site
Fast-prescribing model offers less in-depth clinical workup

Blue Sky MD

What we like

LegitScript certified and physician-led since 2008; one of the most established GLP-1 practices in the Southeast
Compounded semaglutide from $40/week (~$160/month) and tirzepatide from $60/week (~$240/month) — well below brand-name cost
Comprehensive program includes 1-on-1 wellness coaching, nutrition plans, hormone analysis, and a proprietary mobile app
Medication shipped directly to patients’ homes within 3–5 business days; telehealth visits available
Insurance accepted in many cases; affordable self-pay options for uninsured patients

Watch-outs

Geographic reach unclear — physical clinics in NC only; telehealth states beyond NC unconfirmed despite 'from virtually anywhere' claim
Pricing quoted per-week ($40 sema / $60 tirz) rather than per-month; higher-dose pricing not disclosed
Must enroll in full medical weight-loss program to access GLP-1 medications — medication-only Rx not offered
No explicit lab testing protocol published; online FAQ does not confirm labs are included
Small regional provider vs. national platforms; limited provider footprint outside North Carolina

Our Verdict

Winner: 24hrDOC

24hrDOC edges out Blue Sky MD with a higher overall score of 7.1/10 and is particularly strong for Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide. Blue Sky MD remains a solid alternative, especially if you're looking for LegitScript-certified, NC-based; compounded sema $40/wk or tirz $60/wk; physician-led + 1-on-1 coaching.

Choose 24hrDOC if…

You want Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide and a starting price around $149/mo.

Visit 24hrDOC →

Choose Blue Sky MD if…

You want LegitScript-certified, NC-based; compounded sema $40/wk or tirz $60/wk; physician-led + 1-on-1 coaching and a starting price around $160/mo.

Visit Blue Sky MD →

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24hrDOC vs Blue Sky MD: FAQ

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Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Semaglutide · Drugs and brands
Tirzepatide · Drugs and brands
Compounded GLP-1 · Pharmacy and drug forms
503A pharmacy · Pharmacy and drug forms
PCAB accreditation · Pharmacy and drug forms
Prior authorization (PA) · Insurance and regulatory
Off-label use · Insurance and regulatory
FDA Drug Shortage List · Insurance and regulatory

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