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24hrDOC vs Avono Health

An in-depth comparison of two leading GLP-1 Providers

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24hrDOC logo

24hrDOC

7.1
★★★3.6

Best for: Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide

Visit 24hrDOC
VS
Avono Health logo

Avono Health

7.2
★★★3.6

Best for: shoppers who want a wide, transparently priced compounded GLP-1 menu including microdose and oral options

Visit Avono Health

24hrDOC and Avono Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 24hrDOC starts lower at $149/mo versus $179/mo, and Avono Health edges ahead overall (7.2 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

24hrDOC

0.25-2 mg titrated, once weeklyCompounded
$149/mo
semaglutide
Oral semaglutide tabletsCompounded
$309/mo
semaglutide

Avono Health

MicrodoseCompounded
$179/mo
semaglutide

Injection (microdose).

MicrodoseCompounded
$199/mo
semaglutide

Oral dissolving tablets (microdose).

MicrodoseCompounded
$219/mo
tirzepatide

Injection (microdose).

MicrodoseCompounded
$229/mo
tirzepatide

Oral dissolving tablets (microdose).

StandardCompounded
$269/mo
semaglutide

Injection. Bundle discounts at 3/6/12 months.

StandardCompounded
$299/mo
semaglutide

Oral capsules.

StandardCompounded
$349/mo
tirzepatide

Injection. Bundle discounts at 3/6/12 months.

StandardCompounded
$379/mo
tirzepatide

Oral capsules.

What’s included

24hrDOC

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Avono Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

24hrDOC

7.1/10

Overall

Avono Health

7.2/10

Value25%

7.5A
vs
B
7.0

Effectiveness25%

7.0A
vs
B
7.5

User Experience15%

7.0A
vs
B
7.5

Trust & Safety15%

6.5A
vs
B
6.5

Accessibility10%

7.0A
vs
B
7.5

Support10%

7.0A
vs
B
7.5

Features & Coverage

Feature24hrDOCAvono Health
Starting Price$149/mo$179/mo
Features8 features6 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 24hrDOC

24hrDOC is a fast cash-pay telehealth service that prescribes compounded GLP-1 medications for weight loss, including once-weekly semaglutide injections, oral semaglutide tablets, and tirzepatide. Compounded semaglutide runs about 149 dollars per month (from 249), with a 100 dollar first-order discount and doses titrated from 0.25 mg to 2 mg. The model emphasizes speed: a roughly 10-minute assessment, prescriptions within about 45 minutes, unlimited messaging, and discreet shipping from licensed pharmacies. Self-pay only, no insurance, operating 24/7. States served are not listed online.

Read our full 24hrDOC review →

About Avono Health

Fully online compounded GLP-1 telehealth with transparent, tiered pricing — microdose and standard semaglutide and tirzepatide in both injection and oral forms — plus US-licensed clinicians, 24/7 messaging support, and free discreet shipping.

Read our full Avono Health review →

Pros & Cons

24hrDOC

What we like

  • Low compounded semaglutide price, around 149 per month
  • Fast model: 10-minute assessment, Rx within 45 minutes
  • Injectable and oral semaglutide plus tirzepatide options
  • 24/7 availability with unlimited provider messaging

Watch-outs

  • Compounded only, not FDA-approved branded GLP-1s
  • Self-pay only, no insurance accepted
  • States served not disclosed on the site
  • Fast-prescribing model offers less in-depth clinical workup

Avono Health

What we like

  • Transparent tiered pricing from $179/mo (microdose semaglutide injection)
  • Full compounded range — semaglutide and tirzepatide, injection and oral, microdose and standard
  • Free and discreet shipping; 24/7/365 messaging support; 100% online
  • US-licensed clinicians and pharmacies; bundle discounts at 3/6/12 months

Watch-outs

  • Medications are compounded, not FDA-approved brand-name
  • Compounding pharmacy not publicly named
  • State availability not published
  • Newer brand with limited independent review history

Our Verdict

Winner: Avono Health

Avono Health edges out 24hrDOC with a higher overall score of 7.2/10 and is particularly strong for shoppers who want a wide, transparently priced compounded GLP-1 menu including microdose and oral options. 24hrDOC remains a solid alternative, especially if you're looking for Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide.

Choose 24hrDOC if…

You want Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide and a starting price around $149/mo.

Choose Avono Health if…

You want shoppers who want a wide, transparently priced compounded GLP-1 menu including microdose and oral options and a starting price around $179/mo.

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Needle-free and microdosed compounded GLP-1 options with lab-monitored care

8.1

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24hrDOC vs Avono Health: FAQ

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