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1st Optimal vs Woodwork

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
Woodwork logo

Woodwork

7.2
★★★3.6/5

Best for: Low-cost compounded GLP-1 (oral or injectable) on an LGBTQ-focused men's health platform

Visit Woodwork

1st Optimal and Woodwork are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Woodwork starts at $127/mo, and Woodwork edges ahead overall (7.2 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Pricing not publicly listed.

Woodwork

From (48-week plan)Compounded
$127/mo
semaglutide
FromCompounded
$199/mo
tirzepatide

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What’s included

1st Optimal

Inclusions not disclosed.

Woodwork

What the monthly price covers

Medication

Included

Provider visits

Not disclosed

Shipping

Included

Lab work

Included

Coaching

Included

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

Woodwork

7.2/10

Value25%

6.5A
vs
B
7.5

Effectiveness25%

7.0A
vs
B
7.0

User Experience15%

6.5A
vs
B
7.0

Trust & Safety15%

6.5A
vs
B
6.8

Accessibility10%

6.5A
vs
B
7.0

Support10%

7.4A
vs
B
7.9

Features & Coverage

Feature1st OptimalWoodwork
Starting Price$127/mo
Features8 features8 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes
Brand Name
FSA/HSA Accepted✓ Yes
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About Woodwork

Woodwork is a men's health telehealth platform built by Grindr that offers compounded GLP-1 weight-loss medications alongside ED care, with a focus on serving gay and queer men. The weight program includes compounded semaglutide (injection or oral tablet, from $127/month on a 48-week plan), compounded tirzepatide from $199/month, and a microdose option at $134/month. There are no separate consult or membership fees; free shipping, included lab work, and 1-on-1 care coaching come with the plan, which is HSA and FSA eligible and bundles a free Grindr Unlimited subscription.

Read our full Woodwork review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

Woodwork

What we like

  • Low transparent pricing: compounded semaglutide from $127/month, tirzepatide from $199/month, microdose $134/month
  • Compounded semaglutide offered as injection or oral tablet
  • No separate consult or membership fees
  • Free shipping, included lab work, and 1-on-1 care coaching
  • HSA and FSA eligible; bundles a free Grindr Unlimited subscription
  • LGBTQ-focused men's health platform built by Grindr

Watch-outs

  • Compounded GLP-1s are not FDA-approved finished products
  • Cash-pay only — no insurance billing
  • States served are not listed publicly
  • No compounding pharmacy partner named and no LegitScript badge shown
  • Weight loss is secondary to the platform's men's-health/ED focus

Our Verdict

Winner: Woodwork

Woodwork edges out 1st Optimal with a higher overall score of 7.2/10 and is particularly strong for Low-cost compounded GLP-1 (oral or injectable) on an LGBTQ-focused men's health platform. 1st Optimal remains a solid alternative, especially if you're looking for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.

Choose 1st Optimal if…

You want Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.

Choose Woodwork if…

You want Low-cost compounded GLP-1 (oral or injectable) on an LGBTQ-focused men's health platform and a starting price around $127/mo.

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7.4

Breeze Meds

Compounded GLP-1 access with named prescribers and 4-pharmacy network

7.4

Telos Rx

Needle-free and microdosed compounded GLP-1 options with lab-monitored care

8.1

GobyMeds

Budget-conscious shoppers

1st Optimal vs Woodwork: FAQ

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