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1st Optimal vs Super Healthy Rx

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
Super Healthy Rx logo

Super Healthy Rx

6.9
★★★3.5/5

Best for: pending product verification

Visit Super Healthy Rx

1st Optimal and Super Healthy Rx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Super Healthy Rx starts at $299/mo, and Super Healthy Rx edges ahead overall (6.9 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Pricing not publicly listed.

Super Healthy Rx

StartingCompounded
$299/mo
semaglutide
StartingCompounded
$399/mo
tirzepatide

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What’s included

1st Optimal

Inclusions not disclosed.

Super Healthy Rx

What the monthly price covers

Medication

Not disclosed

Provider visits

Not disclosed

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

Super Healthy Rx

6.9/10

Value25%

6.5A
vs
B
7.0

Effectiveness25%

7.0A
vs
B
7.0

User Experience15%

6.5A
vs
B
7.0

Trust & Safety15%

6.5A
vs
B
6.0

Accessibility10%

6.5A
vs
B
7.5

Support10%

7.4A
vs
B
7.4

Features & Coverage

Feature1st OptimalSuper Healthy Rx
Starting Price$299/mo
Features8 features3 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About Super Healthy Rx

Super Healthy Rx (superhealthyrx.com) is operated by Natural Smart Health LLC and offers compounded semaglutide at $299/mo and compounded tirzepatide at $399/mo via fully licensed and insured physicians. Workflow includes a synchronous visit if state law requires.

Read our full Super Healthy Rx review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

Super Healthy Rx

What we like

  • Listed in both competitor directories
  • US board-certified physicians per competitor sources
  • Accredited compounding pharmacies per competitor sources

Watch-outs

  • Stub entry — exact drug formulary, pricing tiers, states served, and pharmacy partners need a YMYL verification pass
  • Confidence is LOW until that pass is done

Our Verdict

Winner: Super Healthy Rx

Super Healthy Rx edges out 1st Optimal with a higher overall score of 6.9/10 and is particularly strong for pending product verification. 1st Optimal remains a solid alternative, especially if you're looking for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.

Choose 1st Optimal if…

You want Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.

Choose Super Healthy Rx if…

You want pending product verification and a starting price around $299/mo.

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1st Optimal vs Super Healthy Rx: FAQ

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