GLP-1 & Weight Loss Clinics in South Dakota

30 NPI-verified obesity-medicine, endocrinology, and bariatric practices across 12 South Dakota cities — sourced directly from the CMS National Provider registry. The directory also lists 37 facility-type clinics and 0 primary-care clinicians statewide whose CMS taxonomy also includes obesity medicine (see the Taxonomy Mix and per-city bands below).

South Dakota at a Glance

NPI-verified clinics
67
CMS national registry
Cities with a listing
12
Across South Dakota
Obesity-medicine + endo (core)
31
Primary taxonomy match
Bariatric surgery practices
30
Surgical taxonomy

Taxonomy Mix

Of the 67 South Dakota practices in this directory, 31 carry a core obesity-medicine or endocrinology taxonomy (1 Obesity Medicine, 30 Endocrinology, Diabetes & Metabolism), 0 are multi-specialty or primary-care clinic facilities, 30 carry a bariatric-surgery taxonomy, 2 carry a bariatric-medicine-adjacent combination taxonomy, 3 are family or internal medicine practices, and 1 are nurse-practitioner or physician-assistant enumerations.

Top Cities by Clinic Count

Cities with at least 3 clinics and 1 named, address-resolved practice have their own dedicated page. Smaller cities are listed below with their clinic count.

CityClinicsCore taxonomy
Sioux Falls4126
Rapid City93
Aberdeen40
Dakota Dunes42
Winner20
Scotland10
Yankton10
Mitchell10
Springfield10
Chamberlain10
Huron10
Freeman10

All South Dakota Cities (12)

Browse all 12 South Dakota cities in this directory A–Z

In-Person vs Telehealth in South Dakota

The clinics in this directory are in-person obesity-medicine, endocrinology, and bariatric-surgery practices — a good fit if you want a local relationship, have complex needs, or need in-person documentation for insurance. Many South Dakota residents instead use a licensed telehealth provider that ships compounded semaglutide or tirzepatide directly to their address. Featured South Dakota telehealth partners:

Featured Partners · South Dakota

Featured GLP-1 providers serving South Dakota

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  1. Top pick
    7.6
    Maximus

    Compounded from

    $249.99/mo

    Save $1,099.01/mo vs Wegovy
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  2. 8.3
    Found

    Compounded from

    $99/mo

    Save $1,250/mo vs Wegovy
    Get started →
  3. 7.4
    Breeze Meds

    Compounded from

    $199/mo

    Save $1,150/mo vs Wegovy
    Get started →
  4. 6.2
    Wellorithm

    Compounded from

    $147/mo

    Save $1,202/mo vs Wegovy
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  5. 8.2
    Gala

    Compounded from

    $149/mo

    Save $937/mo vs Zepbound
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  6. 6.9
    TMates

    Compounded from

    $249/mo

    Save $1,100/mo vs Wegovy
    Get started →
See all 163 GLP-1 providers serving South Dakota ↓

See our full list of GLP-1 telehealth providers serving South Dakota for pricing and reviews, or compare the best semaglutide and tirzepatide providers nationwide.

Frequently Asked Questions

Our directory lists 30 South Dakota practices whose true primary specialty on file is obesity medicine, endocrinology, or bariatric care, plus 37 clinics and medical centers and 0 primary-care clinicians whose CMS record also lists an obesity-medicine or endocrinology taxonomy — 67 in total across 12 South Dakota cities. Every count comes from the CMS National Provider registry (NPPES) taxonomy on file, not a survey of services.
The registry records each practice's specialty taxonomy, not the specific medications it prescribes or its current service menu. Endocrinology, Diabetes & Metabolism is the most common taxonomy bucket among South Dakota listings in this directory (30 of 67 practices). Obesity-medicine and endocrinology practices commonly prescribe GLP-1 medications like semaglutide (Wegovy, Ozempic) and tirzepatide (Zepbound, Mounjaro), but we can't confirm any individual South Dakota clinic's offerings from the registry alone — call the practice directly to confirm availability, pricing, and new-patient status before booking.
It depends on your insurance and the medication. An in-person visit plus a brand-name prescription (Wegovy or Zepbound) can run $1,000-$1,350 per month without insurance, while licensed telehealth providers shipping compounded semaglutide or tirzepatide directly to South Dakota addresses average around $199/month cash-pay. See our full list of GLP-1 telehealth providers serving South Dakota in the "Prefer Telehealth?" section above.
Every listing is sourced from the CMS National Provider registry (NPPES), the federal database of enumerated healthcare providers. Across South Dakota we verified 30 primary-specialty practices, 37 facility-type listings, and 0 primary-care clinicians carrying a secondary obesity-medicine taxonomy this way — Sioux Falls has the most listings of any South Dakota city in the directory, with 41. Listing reflects the taxonomy on file — it is not an endorsement, and not a confirmation of GLP-1 availability, cash-pay pricing, or new-patient status.