Health outcomes & conditions

GLP-1s, Sexual Health, Fertility & Hormones

GLP-1 drugs interact with reproductive and hormonal health in ways patients often have to ask about privately. This cluster brings together the evidence on sex drive and erectile function, testosterone, oral contraceptive absorption, washout periods before conception, PCOS, menopause and hormone therapy — so the practical questions get primary-source answers.

76 research articles · newest update October 2026

Recently updated

Gestational Diabetes and BMI: Causes, Weight Before Pregnancy and GLP-1 Timing

What causes gestational diabetes, how pre-pregnancy BMI and weight change between pregnancies affect risk, why treatment matters, the later type 2 diabetes risk and how to lower it, and what is known about stopping GLP-1 drugs before pregnancy.

12 min read · Updated October 2026

Uterine Fibroids and Body Weight: What the Evidence Shows

Fibroids are hormonally driven and fat tissue makes estrogen, so weight keeps appearing in the conversation. Why the older literature disagreed, and what a five-year ultrasound study of 1,693 women changed about the answer.

7 min read · Updated September 2026

Does an IUD or Nexplanon Cause Weight Gain? Device-by-Device Evidence Review

Hormonal and copper IUD users gain about the same weight over the years. Nexplanon shows a small, inconsistent signal, and Depo-Provera is the one method with consistent weight-gain evidence. What the trials and FDA labels show for each device.

11 min read · Updated September 2026

Does PCOS Cause Weight Gain? Metabolism and Weight-Loss Evidence Review

Women with PCOS gain weight faster, but genetic studies suggest excess weight drives PCOS more than the reverse. What the evidence says about insulin resistance, metabolic rate, why weight loss can feel harder, and what actually helps.

11 min read · Updated September 2026

All 76 articles in this topic

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