Dosage evidence
MOTS-c Dosage: Why There Is No Established Dose
FDA's position on MOTS-c is the strongest statement of absence on this list: it has found no record of anyone being given it, by any route.
Where MOTS-c stands with the FDA
“FDA has not identified any human exposure data on drug products containing MOTs-C administered via any route of administration.”
There is no dose to report
There is no human dose to report. Any figure presented as a MOTS-c protocol is not derived from human data, because FDA states no human exposure data has been identified at all.
We would rather tell you this than publish a number. Pages that rank for “mots-c dosage” routinely state precise-looking figures with no citation attached to them. A number without a source is not more useful than an honest absence — it is less useful, because it looks like it came from somewhere.
Convert your prescribed dose to syringe units
If a clinician has prescribed MOTS-c for you, the number that matters next is how far to draw the syringe — and that depends on how much bacteriostatic water went into the vial, not on the peptide itself.
This converts a dose your prescriber has already given you into a volume and a number of units on a U-100 insulin syringe. It does not suggest a dose, and it does not tell you whether a peptide is appropriate for you. Most research peptides have no FDA-approved dosing, so there is no “standard” number for us to fill in. Doses here are in micrograms (mcg) — confusing mcg with mg is a 1,000-fold error and the single most common way people get this wrong.
Enter the dose your prescriber gave you, in micrograms, to see the volume and syringe units.
Your 5 mg vial in 2 mL of bacteriostatic water is —.
Keep reading
References
- 1.US Food and Drug Administration. Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks — category 2 of the interim policies, and the list of substances nominated but withdrawn. FDA Human Drug Compounding. 2026. https://www.fda.gov/drugs/human-drug-compounding/certain-bulk-drug-substances-use-compounding-may-present-significant-safety-risks
This page reports what regulators and published sources say about MOTS-c. It is not medical advice, not a recommendation to use MOTS-c, and not a dosing instruction. Every source above was opened and read on the date recorded in our data; regulatory status changes, so check the primary source before relying on it.