Lean mass loss
Adverse events on the FDA labels, with the canonical evidence anchors.
Definition
Loss of muscle, bone, and other non-fat tissue with rapid weight loss. STEP-1 DEXA sub-analysis found roughly 39% of weight lost was lean mass. Mitigated with adequate protein and resistance training.
Semaglutide and muscle mass: STEP DEXA sub-analyses →
Definition curated by Weight Loss Rankings — sourced from FDA labels and peer-reviewed PubMed literature, never AI-generated summaries.
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