Half-life

Titration, half-life, washout, and missed-dose practical concepts.

Definition

Time for plasma concentration to fall by half. Semaglutide ~7 days. Tirzepatide ~5 days. Liraglutide ~13 hours (daily dosing). Orforglipron ~36 hours. Determines weekly vs daily dosing and washout timing.

How long does a GLP-1 stay in your system →

Definition curated by Weight Loss Rankings — sourced from FDA labels and peer-reviewed PubMed literature, never AI-generated summaries.

Related terms in Dosing

Titration
Washout period
Missed dose

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