From the FDA label (DailyMed)Verified 2026-07-12

Wegovy Storage & Handling

How to store semaglutide correctly — refrigeration range, room-temperature allowance, and what to do if it's been frozen or left in the light — transcribed from the FDA prescribing information.

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Wegovy Storage at a Glance

Refrigerated (unopened)
36°F to 46°F (2°C to 8°C)
Room-temperature allowance
Single-dose pen/syringe: 46°F to 86°F (8°C to 30°C) for up to 28 days before the cap is removed. FlexTouch single-patient-use pen (after first use): 59°F to 86°F (15°C to 30°C), or refrigerated, for up to 56 days.
Freezing
Do not freeze WEGOVY. Do not use WEGOVY if it has been frozen.
Light
Protect WEGOVY injection from light — keep it in the original carton until you're ready to inject. Do not store next to the refrigerator's cooling element.

Source: Wegovy FDA prescribing information via DailyMed (SetID ee06186f-2aa3-4990-a760-757579d8f77b), Section 16.2 How Supplied/Storage and Handling. Last verified 2026-07-12. This is summary information — read the full label and the patient instructions that came with your prescription.

Handling the pen or vial

Once you start using it: the in-use window is 56 days after first use (FlexTouch pen) / 28 days (single-dose pen or syringe). Mark the date you first used it (on the device or your calendar) so you know exactly when to discard it — the label requires discarding after this window even if medicine remains.

Keep the pen or vial in its original carton whenever possible — this is what protects it from light, and doubles as a place to note the first-use date. Never store a pen with the needle attached between uses.

Traveling with Wegovy

The WEGOVY tablet (a separate, less common formulation) is room-temperature only — 68°F to 77°F (20°C to 25°C), in its original bottle, away from moisture — no refrigeration needed. For the injection pen or syringe, use a cooler bag for refrigerated travel, or plan around the 28-day (pen/syringe) or 56-day (FlexTouch) room-temperature window.

Related Wegovy guides

Wegovy dosing & titration →
The full FDA-label dose schedule, from starting dose to maintenance.
Wegovy side effects →
Common adverse reactions and the boxed warning, from the FDA label.

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Frequently Asked Questions

Store unopened Wegovy in the refrigerator at 36°F to 46°F (2°C to 8°C). Single-dose pen/syringe: 46°F to 86°F (8°C to 30°C) for up to 28 days before the cap is removed. FlexTouch single-patient-use pen (after first use): 59°F to 86°F (15°C to 30°C), or refrigerated, for up to 56 days. Source: FDA label via DailyMed (SetID ee06186f-2aa3-4990-a760-757579d8f77b), Section 16.2, verified 2026-07-12.
Yes, within limits. Single-dose pen/syringe: 46°F to 86°F (8°C to 30°C) for up to 28 days before the cap is removed. FlexTouch single-patient-use pen (after first use): 59°F to 86°F (15°C to 30°C), or refrigerated, for up to 56 days. Once you start that clock, discard it after 56 days after first use (FlexTouch pen) / 28 days (single-dose pen or syringe), even if some medicine remains.
Do not freeze WEGOVY. Do not use WEGOVY if it has been frozen. If you're not sure whether a dose was exposed to freezing temperatures, don't use it — check with your pharmacy about a replacement.
Protect WEGOVY injection from light — keep it in the original carton until you're ready to inject. Do not store next to the refrigerator's cooling element.