From the FDA label (DailyMed)Verified 2026-06-01

Wegovy Dosing & Titration Schedule

The semaglutide starting dose, full titration ladder, maintenance dose, and maximum dose — transcribed from the FDA prescribing information.

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Wegovy Titration Schedule

The step-by-step dose-escalation ladder for Wegovy from the FDA label's Dosage & Administration section (DailyMed SetID ee06186f-2aa3-4990-a760-757579d8f77b). Your prescriber sets your actual schedule — this is the label reference, not medical advice.

StepDoseWhen
10.25 mg once weeklyWeeks 1–4
20.5 mg once weeklyWeeks 5–8
31 mg once weeklyWeeks 9–12
41.7 mg once weeklyWeeks 13–16
52.4 mg once weeklyWeek 17 onward (maintenance)

Source: Wegovy FDA prescribing information via DailyMed (SetID ee06186f-2aa3-4990-a760-757579d8f77b), Section 2 Dosage & Administration. Last verified 2026-06-01. This is summary information — read the full label and follow your prescriber's instructions.

Wegovy Dosing at a Glance

Starting dose
0.25 mg injected subcutaneously once weekly for 4 weeks
Maintenance dose
For weight reduction: 1.7 mg or 2.4 mg (recommended) once weekly. Patients who tolerate 2.4 mg for at least 4 weeks may be increased to a maximum of 7.2 mg once weekly.
Maximum dose
7.2 mg once weekly

How to titrate safely

If you do not tolerate a dose during escalation, your prescriber should consider delaying the escalation for 4 weeks. Do not exceed the recommended escalation schedule.

The guiding principle: only increase the dose if you're tolerating the current one, and slow down (or pause the escalation) if side effects flare. Going up faster than the label schedule does not speed up results — it mostly increases nausea and other GI side effects.

If you miss a dose or can't tolerate a step

Missed a dose? The late-dose window differs by drug. See our GLP-1 missed-dose rules by drug for the exact rule for Wegovy before doubling up or skipping.

Can't tolerate a dose increase? The label allows delaying escalation or staying on a lower dose. Read what to expect at each step on the Wegovy side effects page, then talk to your prescriber before changing your schedule.

Compare every Wegovy provider

A prescriber sets your dose and titration plan before prescribing. See current pricing, verification status, form, and states served across every vetted provider in one place.

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Frequently Asked Questions

The recommended starting dose of Wegovy (semaglutide) is 0.25 mg injected subcutaneously once weekly for 4 weeks. This is the initiation dose from the FDA label (DailyMed SetID ee06186f-2aa3-4990-a760-757579d8f77b); the starting dose is intended to let your body adjust and is generally not the dose that delivers the full effect.
If you do not tolerate a dose during escalation, your prescriber should consider delaying the escalation for 4 weeks. Do not exceed the recommended escalation schedule. Always follow the exact schedule on your prescription — the dose ladder above is the FDA-label escalation, not medical advice for your situation.
The maximum recommended dose of Wegovy per the FDA label is 7.2 mg once weekly. The recommended maintenance dose is For weight reduction: 1.7 mg or 2.4 mg (recommended) once weekly. Patients who tolerate 2.4 mg for at least 4 weeks may be increased to a maximum of 7.2 mg once weekly..
Missed-dose rules differ by drug — see our GLP-1 missed-dose guide for the exact late-dose window. If a dose increase causes side effects, the label allows staying on (or returning to) a lower dose; talk to your prescriber before changing your schedule. See the Wegovy side-effects page for what to expect at each step.