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Data investigation

How Compounded GLP-1 Prices Moved Over the Last 16 Months: Provider-by-Provider Trajectories

We tracked monthly cash prices for compounded semaglutide across the largest telehealth providers from January 2025 onward. Every provider in our tracked set has cut prices — but at very different rates, with the biggest movers converging on a $199 floor.

By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
10 min read·6 citations

Insufficient price history data to render this article.

Frequently Asked Questions

The 12-month direction depends on the provider and dose. Across the providers we track, average compounded semaglutide pricing has been broadly stable to modestly down for entry doses and modestly up for higher doses, with significant per-provider variance. Our live price tracker shows the current numbers; this article documents the per-provider 12-month trajectory in detail.
Several drivers: (1) Wegovy and Zepbound coming off the FDA shortage list in 2025 narrowed the legal grounds for bulk compounding under sections 503A(b)(1)(D) and 503B(a)(2), (2) API supply costs from key suppliers fluctuated, (3) competitive pressure from new entrants, (4) some providers raised prices to reflect new clinical-oversight costs. The post-shortage regulatory environment is the single biggest driver.
No — the period of rapid price compression that characterized 2023-2024 has stabilized. Most providers we track have held prices flat for 6+ months as the post-shortage regulatory and supply-cost picture has settled. Some have raised prices modestly. Patients seeking the absolute lowest entry price should compare current prices in our live tracker rather than relying on older snapshots.
Possibly. The post-shortage regulatory framework limits which compounded preparations can legally be made, and the supply of legal compounded GLP-1 may shrink as providers adjust. Reduced supply with continued demand typically pushes prices up. The single biggest variable is whether FDA enforcement of the shortage-end rules tightens further.
The FDA declared the tirzepatide shortage resolved in December 2024 and the semaglutide injectable shortage resolved on February 21, 2025, and the enforcement-discretion windows that had allowed broad compounding closed in the following months (April to May 2025 for semaglutide). Mass commercial compounding was therefore largely wound down through 2025, shrinking the cheap compounded supply; only narrow patient-specific 503A clinical-necessity compounding remains broadly permitted. At the same time, manufacturer self-pay vials — LillyDirect Zepbound and NovoCare Wegovy — dropped to roughly $349 to $499 per month, which narrowed the price gap that had driven patients to compounded GLP-1 in the first place.
Always verify the price on the provider's own pricing page on the day you sign up — telehealth pricing can change without notice. Our price tracker is updated on a monthly cadence and our pricing database is verified continuously, but the source of truth for any specific transaction is the provider's checkout page.

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Where to get GLP-1 safely: vetted online providers

Vetted telehealth providers that prescribe online. We compare pricing, form, and states served.

No insurance needed · vetted by our editors

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7.1

Bodybuilding Health+

Fitness-brand compounded GLP-1 with hormone and performance programs

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7.4

Luvo Health

Compounded and brand GLP-1s, oral tablets and peptides on one price list

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8.0

Strut Health

Oral-lozenge compounded GLP-1 access

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