From the FDA label (DailyMed)Verified 2026-06-01

Foundayo Dosing & Titration Schedule

The orforglipron starting dose, full titration ladder, maintenance dose, and maximum dose — transcribed from the FDA prescribing information.

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Foundayo Titration Schedule

The step-by-step dose-escalation ladder for Foundayo from the FDA label's Dosage & Administration section (DailyMed SetID 8ac446c5-feba-474f-a103-23facb9b5c62). Your prescriber sets your actual schedule — this is the label reference, not medical advice.

StepDoseWhen
10.8 mg once dailyStarting dose
22.5 mg once dailyAfter at least 30 days on 0.8 mg
35.5 mg once dailyAfter at least 30 days on 2.5 mg
49 mg once dailyAfter at least 30 days, based on response and tolerability
514.5 mg once dailyAfter at least 30 days, based on response and tolerability
617.2 mg once dailyAfter at least 30 days, based on response and tolerability

Source: Foundayo FDA prescribing information via DailyMed (SetID 8ac446c5-feba-474f-a103-23facb9b5c62), Section 2 Dosage & Administration. Last verified 2026-06-01. This is summary information — read the full label and follow your prescriber's instructions.

Foundayo Dosing at a Glance

Starting dose
0.8 mg orally once daily
Maintenance dose
5.5 mg, 9 mg, or 17.2 mg once daily, based on treatment response and tolerability
Maximum dose
17.2 mg once daily

How to titrate safely

Allow at least 30 days on the current dose before each increase. Take once daily with or without food; swallow tablets whole (do not break, crush, or chew). Do not take more than one tablet per day.

The guiding principle: only increase the dose if you're tolerating the current one, and slow down (or pause the escalation) if side effects flare. Going up faster than the label schedule does not speed up results — it mostly increases nausea and other GI side effects.

If you miss a dose or can't tolerate a step

Missed a dose? The late-dose window differs by drug. See our GLP-1 missed-dose rules by drug for the exact rule for Foundayo before doubling up or skipping.

Can't tolerate a dose increase? The label allows delaying escalation or staying on a lower dose. Read what to expect at each step on the Foundayo side effects page, then talk to your prescriber before changing your schedule.

Compare every Foundayo provider

A prescriber sets your dose and titration plan before prescribing. See current pricing, verification status, form, and states served across every vetted provider in one place.

Frequently Asked Questions