Scientific deep-dive

Is Sweating Good for Weight Loss? Honest Evidence Review

Honest answer: no. Sweat is water + electrolytes for thermoregulation, not fat metabolism. Scale drops of 0.5-2 lb after sauna, hot yoga, sweat suits, or long runs are pure water that rehydrates within hours. Magnitude vs GLP-1s is a category error.

By Eli Marsden · Founding Editor
Editorially reviewed (not clinically reviewed) · How we verify contentLast reviewed
13 min read·9 citations

The honest answer: no. Sweating is thermoregulation, not fat metabolism. A 20–60 minute sweaty session drops the scale 0.5–2 lb of water and electrolytes that rehydrate within hours. Saunas, hot yoga, sweat suits, and “heat training” produce no fat loss. Fat loss requires a sustained calorie deficit; heat produces transient water loss plus real dehydration risk.

At a glance

  • Per-session weight loss: ~0.5–1 kg of sweat-mediated water and electrolytes per 20–30 min heat session[1]. Returns within ~24 h of normal rehydration. Endurance athletes can lose 1–2 kg of sweat per hour in hot conditions.
  • What sweat actually is: ~99% water plus sodium, chloride, potassium, and small amounts of magnesium, urea, and lactate. Fat is not a sweat component. The eccrine sweat glands handle thermoregulation; apocrine glands (axilla, groin) handle scent, not heat.
  • Calories burned by sweating itself:essentially none. Heat dissipation costs ~30–80 kcal above resting per ~30-min passive sauna session[2] — less than a slow walk for the same duration.
  • The exercise confound: people who run, cycle, or train hard sweat heavily AND burn meaningful calories. The calories come from the mechanical work, not the sweat. A sauna sitter sweating buckets is doing none of the mechanical work.
  • Sweat suits, plastic bags, weight cuts: the Martinez-Aranda 2023 systematic review[3] documents combat-sports weight cuts of 5–10% body mass in 24–72 hours from sweat-suit / sauna-suit / passive-heat protocols — all dehydration, with measurable performance penalties and a clear heat-illness signal.
  • Acute risks: heat exhaustion, exertional heat stroke (medical emergency, ~107 °F core), orthostatic syncope, and exercise-associated hyponatremia from over-drinking plain water during long heat events[4].
  • GLP-1 multiplier risk: semaglutide and tirzepatide reduce central thirst signaling and produce mild baseline volume depletion[7]. Layering sweat-driven loss on top can drive dizziness, orthostatic hypotension, and rarely pre-renal acute kidney injury.
  • Magnitude vs pharmacotherapy: STEP-1 semaglutide[8] −14.9% body weight at 68 weeks; SURMOUNT-1 tirzepatide[9] −20.9% at 72 weeks. Sweating produces ~0.5 kg of transient water per session. Not comparable interventions.

What sweat actually is (and what it is not)

Sweat is the body’s cooling fluid. By weight it is approximately 99% water plus sodium and chloride (the dominant electrolytes, ~40–60 mmol/L of sodium in unacclimatized sweat, declining with heat acclimatization), potassium (~5–10 mmol/L), small amounts of magnesium and calcium, and trace urea and lactate. It is hypotonic with respect to plasma, meaning the body loses more water than solute per unit volume of sweat.

Fat is not in sweat. There is no biochemical pathway by which adipocyte triglyceride leaves the body through the skin. Fat loss exits the body as carbon dioxide (~84% by mass, via the lungs) and water (~16%, mostly via urine and the breath), following the oxidation pathway documented by Meerman and Brown 2014 BMJ. The water byproduct of fat oxidation can leave the body as sweat, but the volume is trivial relative to the heat-driven sweat output we are talking about. The sweaty workout did not “sweat the fat out.”

Two gland types matter physiologically. Eccrine glands (~2–4 million across the body, densest on palms, soles, and forehead) are the thermoregulatory workhorse — they secrete the hypotonic saltwater that evaporates to cool the skin. Apocrine glands (axilla, groin, perianal) secrete a thicker, lipid- and protein-containing fluid that bacteria metabolize into body odor; they are not thermoregulatory and do not contribute meaningfully to sweat volume during exercise or heat exposure. When marketers say sweating “detoxifies” or “burns fat,” they are conflating the apocrine scent role with the eccrine cooling role and ignoring the liver and kidneys (the actual detoxification organs).

The thermoregulation physiology: sweat is air-conditioning, not exercise

Mammals are obligate homeotherms; we have to keep core temperature within roughly 36–38 °C or enzymes denature. When the hypothalamus senses rising core temperature — from external heat, exercise, fever, or emotional stress — it triggers cutaneous vasodilation (heat leaves through the skin) and eccrine sweat secretion (water evaporates from the skin, taking ~580 kcal of heat per liter with it via the latent heat of vaporization).

That last number is the source of every “sweat burns calories” myth. The 580 kcal/liter is the energy required to evaporate water at body temperature — it is the heat removed from the skin surface, not metabolic energy generated by the body. The actual metabolic cost of producing the sweat in the first place is tiny: a few extra kcal per liter for active secretion. The Hannuksela 2001 Am J Med canonical sauna review[1] and the Hussain and Cohen 2018 systematic review of regular dry-sauna bathing[2] both put the total per-session energy expenditure of a passive heat exposure at the ~30–80 kcal range over resting baseline — less than what you would burn sitting on the couch for the same half hour plus a slow walk to the fridge.

Heart rate rises (~120–150 bpm during sauna) because cardiac output has to drive heat-shedding blood flow to the skin and the dilated vessels need filling. That is not the same as an aerobic training stimulus, although repeated passive heat exposure does produce small cardiovascular adaptations (see the heat-training section below).

Why scale drops from sweating are pure water (and rehydrate within hours)

Run the arithmetic. One pound of body fat is ~3,500 kcal of stored energy. To lose one pound of fat in a single sweaty hour you would have to oxidize 3,500 kcal in 60 minutes — roughly the metabolic rate of an elite cyclist sustaining maximum power for an hour. A person sitting in a sauna, doing hot yoga, or jogging in a sweat suit is doing a tiny fraction of that work. The energy ledger does not balance against fat oxidation.

The ledger that does balance is water. A 70 kg adult carries ~42 kg of total body water (~60% of body mass) split across intracellular, interstitial, and intravascular compartments. Lose 0.5–1 kg of that as sweat in a heat session and the scale reads 1–2 lb lower immediately. Drink ~1 liter of water and eat a normal meal afterward, and the kidneys retain sodium, the gut absorbs water, and the compartments refill. Hannuksela 2001[1] documents the round trip in healthy adults at ~24 hours. Hussain and Cohen 2018[2] synthesizes ~40 dry-sauna trials and reaches the same conclusion: per-session sweat-mediated mass change is transient and reverses with rehydration.

This is the same physiology that drives the “wrestler’s cut,” the diuretic crash, and the sodium-restriction whoosh. We cover the parallel mechanism in our sauna vs steam room evidence review and the broader category in the GLP-1 side effect questions hub. Sweating belongs in the same bucket as those: large, fast, ~100% reversible scale numbers that have nothing to do with adipose tissue.

The “exercise + sweating = fat loss” confound

The single most common reason people associate sweating with fat loss is correlation. Vigorous exercise produces both meaningful energy expenditure AND heavy sweating. The running, cycling, swimming, or HIIT session burns calories because of the mechanical work. The sweat is a byproduct of the heat the working muscles dump. Confusing the byproduct for the cause is the same logical move as crediting the smoke for putting out the fire.

A few clean disambiguations:

  • A heat-acclimatized person sweats faster, earlier, and more dilutely than a sedentary novice at the same workload. Their fat loss at the same workout is not greater — if anything, their thermoregulation is more efficient and they may finish the session less fatigued.
  • The same workout in a 60 °F gym vs an 85 °F studio produces wildly different sweat volumes and roughly the same calorie burn. Body-composition outcomes are not temperature-dependent.
  • A 200 lb person sitting passively in a sauna for 30 min may sweat as much as a 130 lb person running 5K. The runner burned ~400 kcal of real energy; the sauna sitter burned ~50 kcal.
  • If you stop sweating mid-workout (early heat stroke territory — anhidrosis is dangerous), your calorie burn does not stop. The metabolic furnace and the cooling system are decoupled.

See our cycling for weight loss evidence review, the running for weight loss evidence review, and the rowing machine evidence review for what these modalities actually deliver as fat-loss interventions when the calorie ledger — not the towel weight — is doing the work.

Sauna, steam room, and hot yoga: what body-composition trials actually show

The literature on passive heat exposure and body composition is thin because few researchers waste resources testing a null mechanism, but the trials and reviews that exist converge.

Hannuksela and Ellahham 2001[1] document the canonical Finnish sauna response in healthy adults: core temperature rises 0.6–1.2 °C, heart rate climbs to ~120–150 bpm, body weight drops ~0.5 kg per session from sweat, and the weight returns within ~24 hours of normal rehydration. Cardiac output approximately doubles. Peripheral blood vessels dilate. Blood pressure initially rises then falls. None of those adaptations metabolize fat.

The Hussain and Cohen 2018 systematic review[2] synthesizes ~40 RCTs and cohort studies of regular dry-sauna bathing. Documented effects cluster around cardiovascular adaptation, blood-pressure reduction, post-exercise recovery, and inflammatory markers. Fat-mass reduction is not on that list. The reviewers explicitly flag transient body-weight reduction as sweat-mediated and reversible.

Hot yoga gets the same null result. Studies of Bikram and hot vinyasa show meaningful increases in heart rate, sweat volume, and subjective effort vs the same poses at room temperature, but per-session caloric expenditure does not differ enough to drive a body-composition divergence. The heart-rate elevation is largely from the heat stress, not added mechanical work. Practitioners may experience scale drops of 1–3 lb post-session — all water, all back within a day.

See our companion sauna vs steam room evidence review for the broader cardiovascular signal in the Finnish KIHD cohort — meaningful mortality reduction at 4–7 sessions per week, zero weight-loss signal.

Sweat suits, plastic bags, and combat-sports weight cuts: dehydration as a tool, not a fat-loss method

The most aggressive sweating protocols come from combat sports — wrestling, boxing, MMA, judo, jiu-jitsu — where athletes need to make weight for a weigh-in 24–72 hours before competition. The Martinez-Aranda 2023 Int J Environ Res Public Health systematic review[3] synthesizes the modern literature on these protocols. The toolkit includes sweat suits, sauna suits, passive sauna sessions, hot baths, rubber suits over cardio, fluid restriction, and salt restriction. The magnitude is large — cuts of 5–10% of body mass in 24–72 hours are documented — and the mechanism is almost entirely dehydration with a small contribution from glycogen depletion and gut emptying.

Two things are simultaneously true about this approach:

  • It works as advertised for a temporary scale number. The weigh-in number drops by the prescribed amount.
  • It is not fat loss, it carries documented performance penalties (impaired aerobic capacity, anaerobic power, reaction time, and cognitive function vs euhydrated state), and it has caused deaths in the sport. The IOC Tokyo 2020 Adverse Weather Impact working group[6] codifies field management of exertional heat stroke partly because combat-sports and endurance-sports populations remain at elevated risk.

Practical takeaway: if you are not making weight for a sanctioned competition and you are not under athletic- trainer supervision, sweat suits and plastic-bag workouts offer nothing but dehydration risk. They are not a path to sustainable fat loss for any general-population reader.

“Heat training”: real endurance benefit, not a weight-loss tool

Post-workout sauna exposure as a recovery and adaptation modality has real physiologic support. Repeated passive heat exposure produces plasma volume expansion, improved heat tolerance, modest VO2max gains in some studies, and cardiovascular adaptations similar in direction to moderate aerobic training. The Hussain and Cohen 2018 systematic review[2] documents these adaptations across small trials.

Endurance athletes use heat acclimation blocks (5–14 days of daily passive or active heat exposure) before hot races to expand plasma volume and improve performance. These adaptations are real, replicated, and worthwhile if you race in heat. They are not weight-loss adaptations.

The honest reframe: heat exposure is a cardiovascular and recovery tool that may indirectly support a real weight-loss program by supporting training adherence and cardiovascular health. It is not the program. The program is the calorie deficit, the protein intake, the resistance training, and (for many people) the GLP-1.

Magnitude check: sweating vs real weight-loss interventions

Magnitude comparison

Per-session sweat losses across heat modalities are transient water that returns within ~24 h of rehydration (Hannuksela 2001 Am J Med; Hussain 2018 systematic review). The brisk-walk row shows the true energy expenditure of a 30-min walk as kg of fat-equivalent. Compare to 68-72 week pharmacotherapy trials. The y-axis is not on the same scale — the comparison is the point.[1][2][8][9]

  • Sauna 30 min (transient water, returns in 24 h)0.5 kg
    Sweat = water + electrolytes; not fat
  • Hot yoga 60 min (transient water, returns in 24 h)1 kg
    Comparable per-hour sweat to running in heat
  • Sweat-suit combat cut, 24-72 h (transient water)5 kg
    5-10% body mass via dehydration; performance penalty
  • Brisk walk 30 min (true energy expenditure)0.02 kg
    ~150 kcal of real work output
  • STEP-1 semaglutide, 68 wk (% body weight)14.9 % TBWL
    Real fat + lean-mass loss, sustained on therapy
  • SURMOUNT-1 tirzepatide 15 mg, 72 wk (% body weight)20.9 % TBWL
    Largest single non-surgical magnitude
Per-session sweat losses across heat modalities are transient water that returns within ~24 h of rehydration (Hannuksela 2001 Am J Med; Hussain 2018 systematic review). The brisk-walk row shows the true energy expenditure of a 30-min walk as kg of fat-equivalent. Compare to 68-72 week pharmacotherapy trials. The y-axis is not on the same scale — the comparison is the point.

The chart frames the dishonesty of marketing claims that position sweating as a fat-loss mechanism. The first three rows are transient water weight that reverses within hours to days. The brisk-walk row is what 30 minutes of actual mechanical work delivers in fat-equivalent. The bottom two rows are sustained body-composition change over 68–72 weeks of pharmacotherapy. They are not on the same scale — that is the point.

Risks: heat exhaustion, heat stroke, syncope, dehydration, hyponatremia

Aggressive heat exposure — the kind people pursue when they believe sweating equals fat loss — has a non-trivial injury profile. Five clinical pictures cover most cases:

  • Heat exhaustion. Core 38–40 °C (~100–104 °F). Heavy sweating, headache, nausea, weakness, dizziness, tachycardia, cool clammy skin. The NATA position statement summarized by VanScoy 2016[5] describes recognition and management; the treatment is cessation of activity, cool environment, oral or IV rehydration, and reassessment.
  • Exertional heat stroke. Core >40 °C (~104 °F), often higher (~107 °F documented in marathon and military cases). Altered mental status (the critical distinguishing feature from heat exhaustion). MEDICAL EMERGENCY with mortality if not cooled rapidly. The IOC Tokyo 2020 working group[6] documents cold-water immersion as the first-line on-field treatment and rectal temperature as the only accurate field measurement.
  • Heat syncope. Orthostatic fainting from peripheral vasodilation plus volume depletion. Common when standing up rapidly from a sauna bench or after a hot shower. Most cases resolve with horizontal positioning and fluid replacement.
  • Dehydration. The dominant chronic risk of regular heavy sweating. Symptoms scale from lightheadedness and headache through palpitations, oliguria, and (in severe cases) pre-renal acute kidney injury. Hannuksela 2001[1] lists dehydration as the principal acute risk of sauna in deconditioned subjects.
  • Exercise-associated hyponatremia (EAH). The opposite failure mode — drinking too much plain water during a long sweat event, diluting plasma sodium below ~135 mmol/L. The Hew-Butler 2015 consensus statement[4] codifies diagnostic thresholds and emergency management with hypertonic saline; the symptom picture (headache, confusion, seizure) overlaps with heat stroke and is regularly misdiagnosed.

Risk modifiers worth knowing: alcohol amplifies dehydration and blocks the heat-defense vasoconstriction response. Diuretics (HCTZ, furosemide, spironolactone), SGLT-2 inhibitors (Jardiance, Farxiga), ACE inhibitors and ARBs, and beta blockers all interact unfavorably with sweat-driven fluid loss. Age extremes (children, elderly) have less efficient thermoregulation. Pregnancy in the first trimester is conventionally a contraindication to deliberate hyperthermia. Cardiovascular instability (unstable angina, recent MI, severe aortic stenosis, uncontrolled hypertension) is a contraindication to passive heat exposure per Hannuksela 2001[1].

What actually causes fat loss: the calorie-deficit ledger

The substantive answer for any reader who reached this page looking for a faster path: fat loss is a sustained calorie deficit. The body has to oxidize stored triglyceride to meet energy demand it is not getting from food. That oxidation ledger does not care about sweat volume, sauna sessions, or the temperature of the yoga studio. It cares about energy in vs energy out, averaged across days and weeks.

The intervention hierarchy with the strongest evidence in 2026:

  1. GLP-1 / GIP receptor agonists. The largest pharmacological magnitudes outside surgery. Semaglutide 2.4 mg weekly (Wegovy) produced −14.9% body weight at 68 weeks in STEP-1[8]; tirzepatide 15 mg weekly (Zepbound) produced −20.9% at 72 weeks in SURMOUNT-1[9]. Mechanism is appetite suppression, gastric emptying slowdown, and central thirst suppression[7].
  2. Calorie-restricted diet with adequate protein. 0.6–1.0 g protein per pound of target body weight, a 300–500 kcal/day deficit, and consistent tracking. Average 0.5–1.5% body weight per week is realistic and sustainable in most adults.
  3. Resistance training, 2–4 sessions/week. The lean-mass-preservation tool. Does not drive the deficit; protects the body composition under the deficit.
  4. Aerobic activity. Adds the cardiovascular and energy-expenditure dimension. Walking counts. Sweating is a byproduct, not a goal.
  5. Sleep and stress management. Both modulate appetite, food choice, and adherence. Documented but indirect.

Heat exposure does not appear on this list as a fat-loss tool. It can appear as a cardiovascular and recovery adjunct — see the sauna vs steam room evidence review for the case — but that is a different role.

Sweat + GLP-1: the dehydration multiplier readers actually need to know

This is the most clinically important section for our readership. GLP-1 receptor agonists (semaglutide as Wegovy and Ozempic; tirzepatide as Zepbound and Mounjaro; oral semaglutide as Rybelsus; liraglutide as Saxenda) suppress appetite centrally. The Drucker 2024 Cell Metab review[7] documents that GLP-1 receptor signaling in the hypothalamus reduces food intake AND blunts thirst signaling, which combined with reduced overall intake produces mild baseline volume depletion in many patients, particularly during the first 4–8 weeks of titration when GI side effects are at their worst.

Layer sweat-driven fluid loss on top of that baseline and the math gets uncomfortable. A patient running ~6–8 cups of total fluid intake per day loses an additional 0.5–1 kg of fluid in a single sauna or hot-yoga session. Realistic clinical picture:

  • Postural lightheadedness and orthostatic hypotension
  • Tachycardia disproportionate to the activity
  • Headache, fatigue, and worsened nausea
  • Rarely, pre-renal acute kidney injury when combined with NSAID use or pre-existing CKD

Practical guidance for GLP-1 readers:

  • Hydrate before the session: ~500 mL of water in the 30 minutes prior. Use the GLP-1 water intake calculator to set a realistic daily baseline before adding heat exposure.
  • Cap heat sessions at 15–20 minutes during titration. Lengthen only after dose stability and tolerable GI symptoms.
  • Weigh before and after; replace 1.0–1.5 L per kg of weight lost. Add electrolytes (a pinch of salt or a tablet) for sessions >30 min.
  • Avoid sauna and aggressive heat on injection day for the first 4–6 weeks; nausea peaks early in the dosing cycle.
  • Stop and exit if you feel lightheaded, palpitations, or unusual nausea. Lie down with feet elevated and rehydrate slowly. See the broader GLP-1 side effect questions hub for the full constellation of titration-phase patterns.

FAQs

Is sweating good for weight loss?

No, not in any way that matters for fat loss. Sweating is thermoregulation, not energy metabolism. The scale drop after a sweaty session is water and electrolytes that return within hours of normal eating and drinking. Fat loss requires a sustained calorie deficit, not heat exposure.

Why does the scale drop 1–3 pounds after a sauna, hot yoga, or long run?

Pure water and electrolyte loss. Hannuksela & Ellahham 2001[1] document typical per-session body-weight loss of ~0.5 kg from sweat, with the weight returning within ~24 hours of normal rehydration. Endurance athletes can lose 1–2 kg of sweat per hour at high temperatures, but the fat compartment is unchanged.

Does sweating more mean I burned more calories?

No. Sweat volume tracks heat load and individual sweat rate, not energy expenditure. A heat-acclimated athlete sweats more than a sedentary novice doing the same workout. A sauna sitter sweats heavily while burning roughly 30–80 kcal above resting[2]. Calorie burn correlates with mechanical work and metabolic rate, not perspiration.

Do sweat suits, plastic bags, or trash-bag workouts burn fat faster?

No. They produce more sweat by blocking evaporative cooling, which drives transient water loss and meaningful dehydration risk. The Martinez-Aranda 2023 systematic review[3] documents combat-sports weight cuts producing 5–10% body-mass reductions in 24–72 hours, all dehydration-mediated, with measurable performance penalties and a clear heat-injury signal.

Is hot yoga better for weight loss than regular yoga?

Not for fat loss. Hot yoga produces more sweat at the same workload, which produces a larger immediate scale drop. Once you rehydrate, body composition is unchanged compared to the same session at room temperature. Hot yoga has cardiovascular and flexibility benefits; an exclusive fat-loss benefit is not in the evidence.

Can heat training (sauna after workouts) help me lose more fat?

Heat training improves endurance adaptations (plasma volume expansion, heat tolerance, modest VO2max gains in some studies) but the body-composition signal is null. The cardiovascular adaptation is real and worthwhile if you race in heat[2]; the fat-loss reframing is marketing.

What is the actual risk of exercising or sitting in heat?

Heat exhaustion, heat stroke (a medical emergency), syncope, and dehydration in the short term. Exercise- associated hyponatremia from over-drinking during long heat events is a separate emergency covered by the Hew-Butler 2015 consensus[4]. Cold-water immersion is the first-line field treatment for exertional heat stroke per the IOC Tokyo 2020 working group[6].

Can I use a sauna or sweat heavily while taking Wegovy, Ozempic, or Zepbound?

Carefully and with aggressive rehydration. GLP-1 receptor agonists reduce central thirst signaling[7] and many patients already run mild baseline volume depletion. Adding sweat-driven fluid loss on top raises the risk of dizziness, orthostatic hypotension, and rare pre-renal acute kidney injury. Talk to the prescribing clinician before regular heat exposure.

How much water should I drink after a sweaty workout?

Replace 1.0–1.5 L of fluid per kg of body weight lost during the session, ideally by weighing in pre and post. For sessions longer than 60 minutes or in extreme heat, add electrolytes (a pinch of salt or an electrolyte tablet). Plain water alone after very large sweat losses can paradoxically cause hyponatremia[4].

How does sweating compare to a GLP-1 medication for weight loss?

Not on the same scale. STEP-1 semaglutide[8] produced −14.9% body weight at 68 weeks; SURMOUNT-1 tirzepatide[9] produced −20.9% at 72 weeks. Sweating produces ~0.5 kg of transient water per session that returns within a day. Comparing them as weight-loss tools is a category error.

References

  1. 1.Hannuksela ML, Ellahham S. Benefits and risks of sauna bathing. Am J Med. 2001. PMID: 11165553.
  2. 2.Hussain J, Cohen M. Clinical Effects of Regular Dry Sauna Bathing: A Systematic Review. Evid Based Complement Alternat Med. 2018. PMID: 29849692.
  3. 3.Martínez-Aranda LM, Sanz-Matesanz M, Orozco-Durán G, et al. Effects of Different Rapid Weight Loss Strategies and Percentages on Performance-Related Parameters in Combat Sports: An Updated Systematic Review. Int J Environ Res Public Health. 2023. PMID: 36982067.
  4. 4.Hew-Butler T, Rosner MH, Fowkes-Godek S, et al. Statement of the 3rd International Exercise-Associated Hyponatremia Consensus Development Conference, Carlsbad, California, 2015. Br J Sports Med. 2015. PMID: 26227507.
  5. 5.VanScoy RM, DeMartini JK, Casa DJ. National Athletic Trainers' Association Releases New Guidelines for Exertional Heat Illnesses: What School Nurses Need to Know. NASN Sch Nurse. 2016. PMID: 26941054.
  6. 6.Hosokawa Y, Racinais S, Akama T, et al. Prehospital management of exertional heat stroke at sports competitions: International Olympic Committee Adverse Weather Impact Expert Working Group for the Olympic Games Tokyo 2020. Br J Sports Med. 2021. PMID: 33888465.
  7. 7.Drucker DJ. Prevention of cardiorenal complications in people with type 2 diabetes and obesity. Cell Metab. 2024. PMID: 38198966.
  8. 8.Wilding JPH, Batterham RL, Calanna S, Davies M, Van Gaal LF, et al.; STEP 1 Study Group. Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP 1). N Engl J Med. 2021. PMID: 33567185.
  9. 9.Jastreboff AM, Aronne LJ, Ahmad NN, Wharton S, et al.; SURMOUNT-1 Investigators. Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1). N Engl J Med. 2022. PMID: 35658024.