Updated April 12, 2026Expert Reviewed

Best Compounded Semaglutide Providers Ranked & Reviewed

Compounded semaglutide is the budget-friendly path to GLP-1 weight loss. We rank every legitimate telehealth pharmacy offering compounded semaglutide, with verified pricing, sourcing transparency, and independent scores.

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Methodology & sources

Providers in this variant are scored against our published six-factor rubric[1], then filtered to match the specific form shown in the page title. Compounded semaglutide from licensed 503A and 503B pharmacies is legal under federal compounding law[2], and has been historically tolerated while semaglutide has appeared on the FDA Drug Shortage List[3].

Published Phase 3 efficacy for semaglutide 2.4 mg (~14.9% mean weight loss over 68 weeks) comes from the STEP 1 trial[4]. The SURMOUNT-5 head-to-head published in 2025 directly compared tirzepatide and semaglutide[5].

Quick Picks: Top 5

#ProviderScore
1CoreAge Rx9.0Visit
2TrimRx9.0Visit
3Enhance MD8.6Visit
4Noom Med8.6Visit
5Novi8.6Visit

Detailed Reviews

1

CoreAge Rx

Best for: best overall value

9.0

CoreAge Rx offers LegitScript-verified compounded semaglutide and tirzepatide with free 2-day shipping to all 50 states. Backed by licensed physicians and 24/7 support, it delivers the most competitive pricing in the compounded GLP-1 space.

Score Breakdown

Value25%
9.5
Effectiveness25%
8.5
User Experience15%
9
Trust & Safety15%
9
Accessibility10%
9
Support10%
8.5
Starting from $149/mo
Visit CoreAge Rx
2

TrimRx

Best for: best overall value

9.0

Telehealth weight loss provider offering tiered compounded semaglutide programs with both injectable and oral routes, free shipping, and licensed clinician oversight on every prescription.

Score Breakdown

Value25%
9
Effectiveness25%
9
User Experience15%
9
Trust & Safety15%
9
Accessibility10%
9
Support10%
9
Starting from $199/mo
Visit TrimRx
3

Enhance MD

Best for: lab-monitored compounded GLP-1 with mandatory video visit

8.6

Enhance MD pairs compounded semaglutide and tirzepatide with mandatory baseline metabolic labs at Quest Diagnostics and a synchronous video visit with a board-certified clinician — a more rigorous onboarding than the async-only compounded GLP-1 model most telehealth providers use. Three tiers (Core semaglutide, Advanced tirzepatide, Elite combined) plus aggressive intro pricing ($49 first month on Core).

Score Breakdown

Value25%
8.5
Effectiveness25%
8.5
User Experience15%
8.5
Trust & Safety15%
8.5
Accessibility10%
9
Support10%
9
Starting from $49/mo
Visit Enhance MD
4

Noom Med

Best for: psychology + medication combo

8.6

Noom Med integrates GLP-1 medication access with Noom's proven cognitive behavioral therapy curriculum, 1-on-1 dietitian coaching, and dedicated care team — the most comprehensive psychology-plus-medication program available.

Score Breakdown

Value25%
8.5
Effectiveness25%
8
User Experience15%
9
Trust & Safety15%
9
Accessibility10%
9
Support10%
9
Starting from $99/mo
Visit Noom Med
5

Novi

Best for: transparent all-in compounded GLP-1 pricing

8.6

Novi Health International is a Delaware-based telehealth provider offering compounded semaglutide and tirzepatide with all-in transparent pricing — medication, unlimited clinician support, and free 2-day shipping included. No membership fees or hidden add-ons.

Score Breakdown

Value25%
8.5
Effectiveness25%
8.5
User Experience15%
8.5
Trust & Safety15%
8.5
Accessibility10%
9
Support10%
9
Starting from $174/mo
Visit Novi
6

Embody

Best for: lowest first-month entry pricing on compounded GLP-1s

8.5

Embody (Modern Metabolic Medicine) offers compounded semaglutide and tirzepatide via injection plus a unique compounded oral tirzepatide gum formulation. Aggressive first-month entry pricing with all 50 states and a 24/7 clinician messaging model led by a board-certified internal medicine CMO.

Score Breakdown

Value25%
8.5
Effectiveness25%
8.5
User Experience15%
8.5
Trust & Safety15%
8.5
Accessibility10%
8.5
Support10%
8.5
Starting from $99/mo
Visit Embody
7

Strut Health

Best for: oral-lozenge compounded GLP-1 access

8.1

Strut Health offers LegitScript + ACHC-accredited compounded semaglutide and tirzepatide in both injectable and oral lozenge formats, shipping to 49 states. Board-certified US physicians handle prescribing with free unlimited follow-up messaging, but eligibility is gated behind a 'medical necessity' clinician determination that isn't publicly defined.

Score Breakdown

Value25%
8.5
Effectiveness25%
7.5
User Experience15%
8
Trust & Safety15%
8.5
Accessibility10%
8.5
Support10%
8
Starting from $99/mo
Visit Strut Health
8

Get Thin MD

Best for: lowest-priced compounded semaglutide on a 3-month commitment, with brand-name Ozempic/Zepbound also available

7.9

Get Thin MD is a US-based async telehealth platform operated by Get Thin MD LLC, offering compounded semaglutide and tirzepatide injections plus brand-name Ozempic and Zepbound where medically appropriate. Nationwide availability, no insurance or office visits required, with doctor-led personalized plans starting at $169/month on the 3-month compounded semaglutide plan. Alongside GLP-1s the platform also offers sermorelin (muscle growth), NAD+, HRT, and hair-loss treatments — GLP-1 is one vertical within a broader wellness funnel.

Score Breakdown

Value25%
8.5
Effectiveness25%
7.5
User Experience15%
7.5
Trust & Safety15%
7.5
Accessibility10%
8.5
Support10%
7.5
Starting from $169/mo
Visit Get Thin MD
9

HydraMed

Best for: patients wanting all-in pricing with a single intake fee

7.9

HydraMed is a nationwide telehealth platform offering compounded semaglutide, tirzepatide, and a broader peptide menu including PT-141, GHK-Cu, and NAD+ in injection, nasal, and topical forms. All-inclusive monthly pricing covers prescription and supplies, free shipping, and a quick medical questionnaire intake. Compounding is performed at a US FDA-registered pharmacy. Also offers mobile IV services in CO, FL, TN, and WY.

Score Breakdown

Value25%
8
Effectiveness25%
8
User Experience15%
8
Trust & Safety15%
7
Accessibility10%
8.5
Support10%
7.5
Starting from $179/mo
Visit HydraMed
10

PeptidesRx

Best for: patients prioritizing regulatory compliance in the compounded space

7.9

PeptidesRx is a Fort Worth, TX-based licensed telehealth platform offering physician-supervised compounded semaglutide, tirzepatide, and a broader prescription peptide menu. Board-certified medical director, licensed nurse practitioners conducting good-faith examinations, transparent pricing, and shipped directly to patients nationwide. Positions itself as a compliance-focused alternative to gray-market peptide vendors.

Score Breakdown

Value25%
8
Effectiveness25%
8
User Experience15%
7.5
Trust & Safety15%
7.5
Accessibility10%
8
Support10%
8
Starting from $169/mo
Visit PeptidesRx
11

Curex

Best for: affordable compounded GLP-1 with strong corporate transparency and pharmacy testing

7.8

Curex (Curex, Inc.) offers compounded semaglutide ($149/mo) and tirzepatide ($199/mo) in injectable and oral dissolving tablet formats. LegitScript certified. Available in 43+ states. No membership fee. Miami and NYC offices. Originally an allergy immunotherapy company.

Score Breakdown

Value25%
8
Effectiveness25%
7.5
User Experience15%
8
Trust & Safety15%
8
Accessibility10%
8
Support10%
7.5
Starting from $149/mo
Visit Curex
12

Invigor Medical

Best for: patients wanting an established multi-service clinic over a GLP-1-only specialist

7.8

Invigor Medical is a Pasco, WA-based nationwide telehealth provider offering compounded semaglutide and tirzepatide for weight loss alongside peptide therapy and sexual wellness treatments. Established clinic with multi-year operating history and licensed providers in all 50 states.

Score Breakdown

Value25%
7.5
Effectiveness25%
8
User Experience15%
8
Trust & Safety15%
7.5
Accessibility10%
8
Support10%
8
Starting from $199/mo
Visit Invigor Medical
13

NewSelf

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

7.8

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Score Breakdown

Value25%
8.5
Effectiveness25%
7.5
User Experience15%
7.5
Trust & Safety15%
8
Accessibility10%
8
Support10%
7
Starting from $100/mo
Visit NewSelf
14

Precision Telemed

Best for: transparent month-to-month compounded GLP-1 with pharmacy quality documentation

7.8

Precision Telemed (Precision Health Digital LLC) offers compounded semaglutide ($149/mo) and compounded tirzepatide ($199/mo) with month-to-month pricing, no subscription required. LegitScript certified. Available in all 50 states. All medications include Certificate of Analysis confirming potency and purity.

Score Breakdown

Value25%
8
Effectiveness25%
7.5
User Experience15%
7.5
Trust & Safety15%
8
Accessibility10%
8.5
Support10%
7
Starting from $149/mo
Visit Precision Telemed
15

Alan Meds

Best for: budget-conscious shoppers

7.7

Telehealth platform offering compounded semaglutide and tirzepatide with multiple administration formats including microdosing and oral options.

Score Breakdown

Value25%
9
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $99/mo
Visit Alan Meds
16

AmberHealth

Best for: budget-conscious shoppers

7.7

Direct-to-consumer telehealth provider offering some of the lowest compounded GLP-1 pricing on the market.

Score Breakdown

Value25%
9
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $100/mo
Visit AmberHealth
17

Boston Medical Group

Best for: budget-conscious shoppers

7.7

Established medical group offering a 3-month semaglutide weight loss program.

Score Breakdown

Value25%
9
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $66/mo
Visit Boston Medical Group
18

FitRx

Best for: insured patients seeking brand-name GLP-1 access with compounded fallback

7.7

FitRx offers brand-name GLP-1s (Ozempic, Wegovy, Zepbound, Mounjaro) with insurance coordination as low as $25/month, plus compounded semaglutide from $151/month without insurance. LegitScript certified. Available in all 50 states + DC.

Score Breakdown

Value25%
8
Effectiveness25%
7.5
User Experience15%
7.5
Trust & Safety15%
7.5
Accessibility10%
8.5
Support10%
7.5
Starting from $151/mo
Visit FitRx
19

Gimme Care

Best for: affordable compounded GLP-1 with nationwide coverage and microdose options

7.7

Gimme Care offers compounded semaglutide ($130–$160/mo) and compounded tirzepatide ($163–$199/mo) including microdose options. LegitScript verified. Available in all 50 states + DC. No membership fees.

Score Breakdown

Value25%
8
Effectiveness25%
7.5
User Experience15%
7.5
Trust & Safety15%
7.5
Accessibility10%
9
Support10%
7
Starting from $130/mo
Visit Gimme Care
20

Ivim Health

Best for: budget-conscious shoppers

7.7

Telehealth weight loss program with low entry-tier semaglutide pricing and a separate program fee for tirzepatide.

Score Breakdown

Value25%
9
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $75/mo
Visit Ivim Health
21

Lavender Sky Health

Best for: budget-conscious shoppers

7.7

Telehealth weight loss provider with low entry-tier injectable GLP-1 pricing.

Score Breakdown

Value25%
9
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $95/mo
Visit Lavender Sky Health
22

Lemonaid Health

Best for: budget-conscious shoppers

7.7

Telehealth platform offering some of the lowest entry-tier GLP-1 program pricing on the market.

Score Breakdown

Value25%
9
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $348/mo
Visit Lemonaid Health
23

Mochi Health

Best for: budget-conscious shoppers

7.7

Obesity medicine telehealth provider offering aggressively priced compounded GLP-1 programs.

Score Breakdown

Value25%
9
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $138/mo
Visit Mochi Health
24

MyStart Health

Best for: fastest compounded GLP-1 onboarding with a price lock

7.7

MyStart Health offers all-inclusive compounded semaglutide and tirzepatide at $299/month with a price-lock guarantee, same-day physician consultations, and 24/7 care team access. LegitScript certified; Delaware MSO partnering with licensed US clinicians. Best-for: speed of onboarding.

Score Breakdown

Value25%
7.5
Effectiveness25%
7.5
User Experience15%
8
Trust & Safety15%
7
Accessibility10%
8
Support10%
8.5
Starting from $299/mo
Visit MyStart Health
25

OrderlyMeds

Best for: budget-conscious shoppers

7.7

Telehealth provider offering one of the lowest 3-month starter prices for compounded GLP-1 medications.

Score Breakdown

Value25%
9
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $74/mo
Visit OrderlyMeds
26

Pomegranate Health

Best for: budget-conscious shoppers

7.7

Telehealth provider offering some of the lowest compounded GLP-1 pricing on the market.

Score Breakdown

Value25%
9
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $90/mo
Visit Pomegranate Health
27

Trimi Health

Best for: budget-conscious shoppers

7.7

Telehealth provider offering some of the lowest compounded GLP-1 pricing available.

Score Breakdown

Value25%
9
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $99/mo
Visit Trimi Health
28

WeightRx

Best for: budget-conscious shoppers

7.7

Telehealth provider offering one of the lowest monthly prices for compounded semaglutide.

Score Breakdown

Value25%
9
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $83/mo
Visit WeightRx
29

BetterMe Rx

Best for: patients who value pharmacy transparency — six named compounding partners

7.6

BetterMe Rx offers compounded semaglutide ($199/mo) and tirzepatide ($299/mo) in both injectable and oral daily tablet formats. LegitScript verified. All 50 states. Six named pharmacy partners with phone numbers — strongest pharmacy transparency in the dataset.

Score Breakdown

Value25%
7.5
Effectiveness25%
7.5
User Experience15%
7.5
Trust & Safety15%
8
Accessibility10%
8.5
Support10%
7
Starting from $199/mo
Visit BetterMe Rx
30

BeyondMD

Best for: mainstream telehealth GLP-1 access

7.6

Telehealth clinic offering competitively priced compounded semaglutide and tirzepatide.

Score Breakdown

Value25%
8.5
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $139/mo
Visit BeyondMD
31

Found

Best for: mainstream telehealth GLP-1 access

7.6

Personalized weight care platform with a self-pay membership model plus medication costs.

Score Breakdown

Value25%
8.5
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $129/mo
Visit Found
32

GobyMeds

Best for: budget-conscious shoppers

7.6

Affordable telehealth provider offering compounded semaglutide only.

Score Breakdown

Value25%
8.5
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $119/mo
Visit GobyMeds
33

LumiMeds

Best for: mainstream telehealth GLP-1 access

7.6

Telehealth provider with flat-rate compounded GLP-1 pricing on a 3-month plan.

Score Breakdown

Value25%
8.5
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $133/mo
Visit LumiMeds
34

NiceRx

Best for: patients seeking batch-tested compounded GLP-1 with transparent entity disclosure

7.6

NiceRx (NiceRx LLC) offers compounded semaglutide ($199/mo) and compounded tirzepatide ($299/mo) with first-month promos. LegitScript approved. Available in 46 states (not AK, MS, NJ, KS). Founded 2022 by Rob Stransky. Every batch tested for sterility and potency.

Score Breakdown

Value25%
7.5
Effectiveness25%
7.5
User Experience15%
7.5
Trust & Safety15%
8
Accessibility10%
8
Support10%
7
Starting from $199/mo
Visit NiceRx
35

Piper

Best for: mainstream telehealth GLP-1 access

7.6

Telehealth weight loss provider offering competitively priced compounded GLP-1 medications.

Score Breakdown

Value25%
8.5
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $135/mo
Visit Piper
36

Try Yucca Health

Best for: mainstream telehealth GLP-1 access

7.6

Telehealth provider offering competitively priced compounded GLP-1 medications.

Score Breakdown

Value25%
8.5
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $146/mo
Visit Try Yucca Health
37

Vaylen

Best for: GLP-1-focused care with oral and injectable options across all 50 states

7.6

Vaylen is a pure GLP-1 specialist offering compounded semaglutide ($179/mo), compounded tirzepatide ($239/mo), compounded oral GLP-1 ($259/mo), and brand-name Ozempic, Zepbound, and Wegovy. LegitScript certified. Licensed clinicians in all 50 states.

Score Breakdown

Value25%
7
Effectiveness25%
7.5
User Experience15%
8
Trust & Safety15%
7.5
Accessibility10%
8.5
Support10%
7.5
Starting from $179/mo
Visit Vaylen
38

Effecty

Best for: nationwide compounded semaglutide with brand-name fallback

7.5

Effecty offers compounded GLP-1 injections ($160–$205/mo) plus brand-name Ozempic, Wegovy, Zepbound, and Mounjaro. LegitScript certified. Ships to all states nationwide. No membership fees.

Score Breakdown

Value25%
7.5
Effectiveness25%
7.5
User Experience15%
7.5
Trust & Safety15%
7.5
Accessibility10%
8
Support10%
7
Starting from $160/mo
Visit Effecty
39

Sprout Health

Best for: LegitScript-verified compounded GLP-1 via named pharmacies

7.5

Sprout Health Partners offers LegitScript-certified compounded semaglutide ($249/mo) and tirzepatide ($299/mo) via a quiz-first telehealth flow with licensed clinician review, shipping compounded medication from Foothills Pharmacy or Promise Pharmacy.

Score Breakdown

Value25%
7.5
Effectiveness25%
7.5
User Experience15%
7.5
Trust & Safety15%
7.5
Accessibility10%
7.5
Support10%
7.5
Starting from $249/mo
Visit Sprout Health
40

Alloy

Best for: women in menopause/perimenopause who want a Menopause Society-certified clinician AND the broadest brand+compounded GLP-1 formulary in our directory

7.4

Alloy (myalloy.com) is a menopause-focused telehealth brand whose Weight Care program offers brand-name Zepbound (from $349/mo), brand-name Wegovy (from $199/mo), oral Wegovy (semaglutide pill), compounded semaglutide, compounded tirzepatide, and compounded liraglutide (from $80/mo). Initial consultation is $49 (separate from medication cost). All consulting doctors are certified by The Menopause Society. Available in 48 states (not Louisiana or Mississippi for the Weight Care program).

Score Breakdown

Value25%
7.5
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7.5
Accessibility10%
7.5
Support10%
7.5
Starting from $80/mo
Visit Alloy
41

Amble

Best for: mainstream telehealth GLP-1 access

7.4

Telehealth weight loss provider offering compounded semaglutide and tiered tirzepatide programs.

Score Breakdown

Value25%
8
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $179/mo
Visit Amble
42

Care Bare Rx

Best for: LGBTQ+-inclusive compounded GLP-1 telehealth

7.4

Care Bare Rx is an LGBTQ+-inclusive telehealth brand offering compounded semaglutide and tirzepatide starting at $199/month across all 50 states plus Puerto Rico, with brand-name Ozempic also available. Operates on the shared Lion MD clinician + 4-pharmacy network with Breeze Meds and Synergy Rx.

Score Breakdown

Value25%
7.5
Effectiveness25%
7
User Experience15%
7.5
Trust & Safety15%
7
Accessibility10%
8.5
Support10%
7
Starting from $199/mo
Visit Care Bare Rx
43

Hers

Best for: mainstream telehealth GLP-1 access

7.4

Women-focused telehealth brand from Hims and Hers offering compounded semaglutide on a 6-month plan.

Score Breakdown

Value25%
8
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $199/mo
Visit Hers
44

Hims

Best for: mainstream telehealth GLP-1 access

7.4

Major men's telehealth brand offering compounded semaglutide weight loss on a 6-month plan.

Score Breakdown

Value25%
8
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $199/mo
Visit Hims
45

Ivologist

Best for: patients seeking contract-free compounded GLP-1 with nationwide coverage

7.4

Ivologist offers compounded semaglutide and tirzepatide starting at $33/week (12-week plans). LegitScript certified. Available in all 50 states. Also offers hormone therapy, hair regrowth, IV therapy, and longevity treatments. Over 20,000 patients served.

Score Breakdown

Value25%
7.5
Effectiveness25%
7
User Experience15%
7.5
Trust & Safety15%
7.5
Accessibility10%
8.5
Support10%
7
Starting from $145/mo
Visit Ivologist
46

Ivy Rx

Best for: mainstream telehealth GLP-1 access

7.4

Telehealth provider offering tiered compounded semaglutide and tirzepatide programs.

Score Breakdown

Value25%
8
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $175/mo
Visit Ivy Rx
47

Nurx

Best for: mainstream telehealth GLP-1 access

7.4

Established women's telehealth brand offering tiered GLP-1 weight loss programs.

Score Breakdown

Value25%
8
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $179/mo
Visit Nurx
48

ShedRx

Best for: mainstream telehealth GLP-1 access

7.4

Telehealth provider offering compounded GLP-1 medications in injectable, lozenge, and drop formats.

Score Breakdown

Value25%
8
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $199/mo
Visit ShedRx
49

SkinnyRx

Best for: mainstream telehealth GLP-1 access

7.4

Telehealth weight loss provider offering compounded semaglutide.

Score Breakdown

Value25%
8
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $199/mo
Visit SkinnyRx
50

Synergy Rx

Best for: broadest drug catalog in the Lion MD white-label cluster

7.4

Synergy Rx (CareGLP platform, synergyrx.co) is a Wyoming-registered telehealth platform serving 50,000+ patients with compounded semaglutide ($199), tirzepatide ($349), and brand-name Ozempic ($499), Wegovy ($947), and Mounjaro ($947). Runs on the shared Lion MD clinician + 4-pharmacy network with Breeze Meds and Care Bare Rx.

Score Breakdown

Value25%
7.5
Effectiveness25%
7
User Experience15%
7.5
Trust & Safety15%
7.5
Accessibility10%
8.5
Support10%
7
Starting from $199/mo
Visit Synergy Rx
51

Tonik Wellness

Best for: patients who want lab-required clinical GLP-1 care with named pharmacy partners and transparent multi-month pricing

7.4

Tonik Wellness (Tonik Wellness, LLC) offers compounded semaglutide ($149–$225/mo) and compounded tirzepatide ($229–$349/mo) with tiered monthly/quarterly/annual pricing. LegitScript verified. Lab work + video visit required. Partners with Strive Pharmacy and Olympia Pharmacy. Named medical director (Joel Jones, DO) and clinical director (Shawn Thurston, FNP). Broader men's health / longevity platform also offering TRT, peptides, and metabolic therapies.

Score Breakdown

Value25%
7.5
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7.5
Accessibility10%
7
Support10%
7.5
Starting from $149/mo
Visit Tonik Wellness
52

WeightCare

Best for: patients prioritizing pharmacy quality standards (PCAB) with coaching support

7.4

WeightCare offers compounded semaglutide ($249–$399/mo) and tirzepatide ($349/mo) dispensed by FDA-registered, PCAB-accredited pharmacies. Based in Ft. Lauderdale, FL. Claims 85,000+ members since 2022. Quality testing documentation (potency + sterility per USP 797).

Score Breakdown

Value25%
7
Effectiveness25%
7.5
User Experience15%
7.5
Trust & Safety15%
8
Accessibility10%
7
Support10%
7.5
Starting from $249/mo
Visit WeightCare
53

Breeze Meds

Best for: compounded GLP-1 access with named prescribers and 4-pharmacy network

7.3

Breeze Meds is a Georgia-based telehealth provider offering compounded semaglutide ($199/mo), tirzepatide ($399/mo), and NAD+ ($169/mo) across all 50 states. LegitScript certified; named medical team (Dr. Ana Lisa Carr MD, Dr. Kelly Tenbrink MD) and a 4-pharmacy compounding network (Belmar, Strive, Epiq Scripts, Casa Pharma Rx) via Lion MD.

Score Breakdown

Value25%
7.5
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
8.5
Support10%
7
Starting from $199/mo
Visit Breeze Meds
54

RNK Health

Best for: compounded GLP-1 buyers also interested in NAD+, peptide, or longevity add-ons in the same provider relationship

7.3

RNK Health (myrnk.com) is a GLP-1 + longevity telehealth platform offering compounded tirzepatide, compounded semaglutide (injectable and oral), NAD+ (injectable, nasal, liposomal), sermorelin, enclomiphene, and a DNA Blueprint test panel. Medical operations are based in Des Moines, IA; pharmacy fulfillment is in Springville, UT.

Score Breakdown

Value25%
7.5
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7
Support10%
7
Starting from $197/mo
Visit RNK Health
55

Bliv

Best for: mainstream telehealth GLP-1 access

7.2

Telehealth provider focused on personalized GLP-1 weight loss programs.

Score Breakdown

Value25%
7
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $58/mo
Visit Bliv
56

DudeMeds

Best for: men seeking no-fee GLP-1 access with oral and injectable options

7.2

DudeMeds is a men's telehealth platform offering semaglutide and tirzepatide in both oral and injectable formats from $149/month. No membership fee, no doctor fee, free shipping. Also offers TRT, ED, and hair loss treatments. Accepts clinic-switch patients from existing GLP-1 and TRT providers.

Score Breakdown

Value25%
7.5
Effectiveness25%
7
User Experience15%
7.5
Trust & Safety15%
6.5
Accessibility10%
7.5
Support10%
7.5
Starting from $149/mo
Visit DudeMeds
57

Eden

Best for: mainstream telehealth GLP-1 access

7.2

Premium telehealth platform with promotional first-month pricing on both semaglutide and tirzepatide.

Score Breakdown

Value25%
7
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $189/mo
Visit Eden
58

Fitish

Best for: all-inclusive compounded GLP-1 with nationwide shipping

7.2

Fitish offers compounded semaglutide ($219/28 days) and compounded tirzepatide ($339/28 days) including consultation and shipping. LegitScript certified. Ships to all US states. Also offers GLP-1 microdosing.

Score Breakdown

Value25%
7
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
7.5
Accessibility10%
8
Support10%
7
Starting from $219/mo
Visit Fitish
59

Henry Meds

Best for: mainstream telehealth GLP-1 access

7.2

Established compounded GLP-1 telehealth provider offering both injectable and oral formats.

Score Breakdown

Value25%
7
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $249/mo
Visit Henry Meds
60

Independent Wellness

Best for: mainstream telehealth GLP-1 access

7.2

Telehealth wellness clinic offering GLP-1 medications on a 4-week billing cycle.

Score Breakdown

Value25%
7
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $249/mo
Visit Independent Wellness
61

MEDVi

Best for: mainstream telehealth GLP-1 access

7.2

Telehealth weight loss provider offering compounded GLP-1 medications with promotional first-month pricing.

Score Breakdown

Value25%
7
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $179/mo
Visit MEDVi
62

OnlineSemaglutide.org

Best for: mainstream telehealth GLP-1 access

7.2

Telehealth provider offering compounded semaglutide in both injectable and oral pill formats.

Score Breakdown

Value25%
7
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $150/mo
Visit OnlineSemaglutide.org
63

Peak Wellness

Best for: mainstream telehealth GLP-1 access

7.2

Telehealth wellness provider offering compounded GLP-1 medications with promotional first-month pricing.

Score Breakdown

Value25%
7
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $129/mo
Visit Peak Wellness
64

Queen RX

Best for: budget-conscious patients seeking low-cost compounded GLP-1

7.2

Queen RX offers compounded GLP-1 treatment (semaglutide, tirzepatide, liraglutide) at $299/quarter (~$100/mo). Available in 45 states (not KS, LA, MS, NM, WV).

Score Breakdown

Value25%
8
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
6
Accessibility10%
7.5
Support10%
7
Starting from $100/mo
Visit Queen RX
65

ReadyRx

Best for: compounded GLP-1 buyers who want LegitScript certification and explicit batch lab testing claims at a sub-$200 starting price

7.2

ReadyRx (readyrx.com) is a LegitScript-certified US telehealth provider offering compounded semaglutide from $179/mo and compounded tirzepatide from $255/mo, plus NAD+, sermorelin, glutathione, MIC+B12, and metformin. Marketed as serving 5,000+ members across all 50 states with batch lab testing for potency, sterility, pH, and endotoxicity.

Score Breakdown

Value25%
7.5
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $179/mo
Visit ReadyRx
66

Remedy Meds

Best for: mainstream telehealth GLP-1 access

7.2

Telehealth provider offering compounded semaglutide and tirzepatide programs.

Score Breakdown

Value25%
7
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $299/mo
Visit Remedy Meds
67

Willow

Best for: mainstream telehealth GLP-1 access

7.2

Telehealth provider offering compounded GLP-1 medications in both tablet and injectable formats.

Score Breakdown

Value25%
7
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $299/mo
Visit Willow
68

AgelessRx

Best for: longevity-focused GLP-1 care (pending verification)

7.1

AgelessRx is an Ann Arbor, Michigan-based longevity and GLP-1 telehealth platform offering compounded semaglutide, compounded tirzepatide, and brand-name Wegovy. Positioned as a longevity-first brand with GLP-1 as one of several metabolic health offerings.

Score Breakdown

Value25%
7
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $199/mo
Visit AgelessRx
69

Fella Health

Best for: men's weight loss

7.1

Fella Health is a medication weight loss program built specifically for men, offering compounded GLP-1 treatments (semaglutide and tirzepatide) plus free 1:1 health coaching, board-certified clinician care, and a 6-month money-back guarantee. Headquartered in Austin, TX.

Score Breakdown

Value25%
6
Effectiveness25%
7.5
User Experience15%
7.5
Trust & Safety15%
7.5
Accessibility10%
6.5
Support10%
8
Starting from $165/mo
Visit Fella Health
70

Healthicare

Best for: buyers who want a transparent, named-clinician + named-pharmacy compounded GLP-1 option in 44 states

7.1

Healthicare (healthicare.com) is a GLP-1 telehealth offering compounded semaglutide from $147.90/mo and compounded tirzepatide from $224.40/mo, plus brand-name Ozempic, Wegovy, Mounjaro, and Zepbound from $1,199.99–$1,299.99 first month. Available in 44 US states (excludes CA, NV, NJ, NC, TX, MA, MS, NH, WV, DE). Clinical operations are run by Beluga Health (named clinician: Dr. Jonah Mink) and prescriptions are dispensed by F&F Pharmacies Inc. dba Jungle Jim's Pharmacy in Fairfield, OH.

Score Breakdown

Value25%
7.5
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
6.5
Accessibility10%
7
Support10%
7
Starting from $148/mo
Visit Healthicare
71

MangoRx

Best for: pending product verification

7.1

MangoRx (Mangoceuticals) is a men's health telehealth platform offering compounded GLP-1 weight management alongside testosterone replacement therapy, ED treatment, and hair loss programs. Stub entry pending YMYL verification of the GLP-1-specific offering — pricing, states, pharmacy partners, and clinical workflow.

Score Breakdown

Value25%
7
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $199/mo
Visit MangoRx
72

NativeMed

Best for: buyers comfortable with sub-$200 promotional compounded GLP-1 pricing who can verify pharmacy partner identity directly with NativeMed support before subscribing

7.1

NativeMed, LLC (nativemed.net) is a Miami, FL-based cash-pay telehealth provider offering compounded semaglutide at promotional $149/mo (regular $299) and compounded tirzepatide at promotional $183/mo (regular $399), plus NAD+ and several non-weight-loss generics. LegitScript certified.

Score Breakdown

Value25%
7
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $149/mo
Visit NativeMed
73

Priority Meds

Best for: pending product verification

7.1

Priority Meds LLC (prioritymeds.com), 13575 58th St N Ste 200, Clearwater, FL 33760, is a 100% online, flat-dose-pricing cash-pay telehealth provider offering compounded semaglutide ($98.99–$112.99/mo with B12) and compounded tirzepatide ($170.99/mo with B6). All dosages billed at the same price across the escalation schedule.

Score Breakdown

Value25%
7
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $113/mo
Visit Priority Meds
74

Super Healthy Rx

Best for: pending product verification

7.1

Super Healthy Rx (superhealthyrx.com) is operated by Natural Smart Health LLC and offers compounded semaglutide at $299/mo and compounded tirzepatide at $399/mo via fully licensed and insured physicians. Workflow includes a synchronous visit if state law requires.

Score Breakdown

Value25%
7
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $299/mo
Visit Super Healthy Rx
75

Actin

Best for: affordable compounded semaglutide with B12 enhancement

7.0

Actin offers compounded semaglutide with B12 for weight loss. Also provides hormone, sexual wellness, and hair health treatments. Transparent pricing starting from $133.

Score Breakdown

Value25%
7
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7
Support10%
7
Starting from $133/mo
Visit Actin
76

Freya Meds

Best for: patients wanting dietitian-supported compounded GLP-1 programs

7.0

Freya Meds is a GLP-1 specialist offering compounded semaglutide ($250–$297/mo) and compounded tirzepatide ($332–$390/mo). Includes unlimited doctor consultations, monthly group calls, and dietitian consultation. Claims 450,000+ enrolled.

Score Breakdown

Value25%
7
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7
Support10%
7
Starting from $250/mo
Visit Freya Meds
77

HealthOn

Best for: compounded GLP-1 access

7.0

HealthOn offers compounded semaglutide and tirzepatide starting at $155/month. Multi-category telehealth platform covering weight loss, sexual health, longevity, and hair health.

Score Breakdown

Value25%
7
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7
Support10%
7
Starting from $155/mo
Visit HealthOn
78

HeliMeds

Best for: affordable compounded semaglutide with brand-name fallback options

7.0

HeliMeds offers compounded semaglutide and tirzepatide as well as brand-name Wegovy and Zepbound. LegitScript certified (#368688). Also provides sexual health and energy treatments.

Score Breakdown

Value25%
7
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7
Support10%
7
Starting from $99/mo
Visit HeliMeds
79

Joi and Blokes

Best for: patients wanting lab-required clinical GLP-1 programs with multiple drug options

7.0

Joi and Blokes offers compounded GLP-1/GIP ($199/mo), brand-name liraglutide ($299/mo), and brand-name Zepbound ($99/mo + med cost, quarterly). Separate men's and women's health divisions with hormone therapy, weight loss, and wellness programs. Lab + clinician visit required for all weight loss medications.

Score Breakdown

Value25%
7
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7
Support10%
7
Starting from $199/mo
Visit Joi and Blokes
80

Lyfe Rx

Best for: use with caution — FDA warning letter on file

7.0

Lyfe Rx offers compounded semaglutide ($289) and compounded tirzepatide ($399). Ships to all 50 states. CAUTION: FDA warning letter issued 09/09/2025 for misbranding compounded GLP-1 products.

Score Breakdown

Value25%
7
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7
Support10%
7
Starting from $289/mo
Visit Lyfe Rx
81

Maximus Tribe

Best for: men seeking compounded GLP-1 alongside testosterone optimization

7.0

Maximus is a men's health platform offering compounded semaglutide (from ~$99/mo) and compounded tirzepatide alongside testosterone replacement therapy and longevity treatments. Available in all 50 states + DC. Microdose protocol available for patients with less weight to lose.

Score Breakdown

Value25%
7
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7
Support10%
7
Starting from $80/mo
Visit Maximus Tribe
82

Midi Health

Best for: women in menopause / perimenopause with commercial insurance who want GLP-1 prescribing as part of a broader hormone + metabolic care plan, not as a standalone weight-loss product

7.0

Midi Health is a nationwide 50-state menopause and perimenopause telehealth platform. GLP-1 prescribing is offered as a clinician-discretionary metabolic-health adjunct within the menopause care framework — not as a standalone weight-loss product. Accepts commercial insurance but does NOT accept Medicare, Medicaid, or Medi-Cal.

Score Breakdown

Value25%
7
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
6.5
Support10%
7
Starting from $128/mo
Visit Midi Health
83

NexLife

Best for: pharmacy-quality-conscious patients seeking LegitScript + NABP-certified compounded GLP-1

7.0

NexLife is a LegitScript-certified telehealth platform offering compounded semaglutide (from $145/mo) and compounded tirzepatide (from $186/mo). Works exclusively with LegitScript-certified, NABP-accredited pharmacies.

Score Breakdown

Value25%
7
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7
Support10%
7
Starting from $145/mo
Visit NexLife
84

PlushCare

Best for: readers who want a primary-care relationship with GLP-1 prescribing as one option, AND who read the class-action disclosure and verify the cancellation flow before subscribing

7.0

Established virtual primary-care telehealth platform (subsidiary of Transcarent, Inc., a Delaware corporation, alongside Accolade, 2nd.MD, and 98point6 by Transcarent). PlushCare offers virtual visits with US board-certified physicians at $30 insured / $129 self-pay per appointment, with GLP-1 prescribing as a clinician-discretionary option within the broader primary-care relationship.

Score Breakdown

Value25%
7.5
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
5.5
Accessibility10%
7.5
Support10%
7
Starting from $149/mo
Visit PlushCare
85

Roen Rx

Best for: patients with insurance seeking brand-name GLP-1 access with compounded fallback

7.0

Roen Rx offers compounded semaglutide as well as brand-name Ozempic, Wegovy, Zepbound, and Mounjaro with insurance coordination. LegitScript approved. Insurance-covered brand GLP-1s as low as $25/mo; compounded semaglutide from $151/mo quarterly.

Score Breakdown

Value25%
7
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7
Support10%
7
Starting from $151/mo
Visit Roen Rx
86

Vyora Wellness

Best for: patients wanting coaching-inclusive compounded GLP-1 programs

7.0

Vyora Wellness offers compounded semaglutide ($299/mo) and compounded tirzepatide ($399/mo) as 4-week subscription plans. LegitScript certified. Price includes GLP-1 nutritional guidance, 24/7 coaching, and community access. BMI 25+ required.

Score Breakdown

Value25%
7
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7
Support10%
7
Starting from $299/mo
Visit Vyora Wellness
87

Wisp

Best for: buyers who want a board-certified telehealth platform offering both branded injectables AND a sublingual alternative — with full disclosure that the sublingual form is not human-tested

7.0

Wisp (hellowisp.com) is a US telehealth provider whose weight care vertical offers brand-name Wegovy, Zepbound, and Saxenda alongside a compounded sublingual semaglutide drops formulation at $225/month. Reviews are completed by board-certified providers within 24-72 hours. Wisp is LegitScript certified.

Score Breakdown

Value25%
7
Effectiveness25%
6.5
User Experience15%
7.5
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $225/mo
Visit Wisp
88

Mojoon

Best for: comprehensive concierge care

6.9

Premium-priced telehealth provider offering compounded semaglutide.

Score Breakdown

Value25%
6
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $450/mo
Visit Mojoon
89

ReflexMD

Best for: comprehensive concierge care

6.9

Telehealth weight loss provider with promotional first-month pricing and flat all-inclusive program rates.

Score Breakdown

Value25%
6
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $297/mo
Visit ReflexMD
90

Sesame

Best for: mainstream telehealth GLP-1 access

6.9

Direct-pay telehealth marketplace offering GLP-1 weight loss with promotional pricing on the first two months.

Score Breakdown

Value25%
6
Effectiveness25%
7.5
User Experience15%
7
Trust & Safety15%
7
Accessibility10%
7.5
Support10%
7
Starting from $199/mo
Visit Sesame
91

Concierge MD LA

Best for: patients in major cities wanting concierge in-home GLP-1 access

6.8

Concierge MD LA offers semaglutide ($199/mo) and tirzepatide ($299/mo) alongside brand-name Ozempic, Mounjaro, Zepbound, and Wegovy ($1,999/mo each). In-home and telemedicine services available in LA, NY, and 25+ cities.

Score Breakdown

Value25%
6.5
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
6.5
Accessibility10%
6.5
Support10%
7
Starting from $199/mo
Visit Concierge MD LA
92

Elevated Health

Best for: affordable compounded GLP-1 with oral option

6.8

Elevated Health offers compounded semaglutide ($176/mo) and compounded tirzepatide ($238/mo). $100 off first month promotional offer. Also offers oral semaglutide.

Score Breakdown

Value25%
7
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
6
Accessibility10%
7
Support10%
6.5
Starting from $176/mo
Visit Elevated Health
93

Levers Health

Best for: patients interested in GLP-1 microdosing for longevity

6.8

Levers Health (Levers Health LLC) offers compounded semaglutide (from $247/mo) and tirzepatide (from $296/mo), plus low-dose/microdose GLP-1 for longevity. Positioned as personalized performance medicine.

Score Breakdown

Value25%
6.5
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
6.5
Accessibility10%
7
Support10%
7
Starting from $246/mo
Visit Levers Health
94

FuturHealth

Best for: readers who want both brand-name and compounded GLP-1 options on one platform with registered-dietitian nutrition coaching, AND are willing to read the data-breach litigation disclosure before signing up

6.7

FuturHealth Inc. is a San Diego-based telehealth weight management brand offering brand-name Ozempic, Wegovy, Mounjaro, and Zepbound plus clinician-discretionary compounded GLP-1/GIP combinations, dispensed through US-based licensed pharmacies. The platform layers digital coaching and registered-dietitian nutrition guidance on top of the medication.

Score Breakdown

Value25%
6.5
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
5.5
Accessibility10%
7.5
Support10%
7
Starting from $199/mo
Visit FuturHealth
95

Injectco

Best for: Dallas-area patients seeking bulk GLP-1 pricing from an established medspa

6.7

Injectco is a Dallas-based medspa offering compounded GLP-1 prescriptions shipped from licensed US partner pharmacies. $1,249 for 6-8 month supply at starting dose (as low as $156/mo on payment plan). Founded July 2021.

Score Breakdown

Value25%
7
Effectiveness25%
7
User Experience15%
6.5
Trust & Safety15%
6.5
Accessibility10%
6
Support10%
7
Starting from $156/mo
Visit Injectco
96

AMP Health

Best for: patients wanting oral semaglutide with coaching support

6.6

AMP Health offers compounded semaglutide (injectable and oral) from $199/mo and tirzepatide from $309/mo, plus a $79/mo subscription fee. Brand Wegovy listed but out of stock. 30-day satisfaction guarantee.

Score Breakdown

Value25%
6
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
6
Accessibility10%
7
Support10%
7
Starting from $199/mo
Visit AMP Health
97

Arc-1

Best for: patients seeking per-dose compounded GLP-1 without subscriptions

6.4

Arc-1 offers compounded semaglutide (from $249.99) and compounded tirzepatide (from $299.99) as per-dose purchases, not monthly subscriptions. Longevity-focused platform also offering ED medication, B12, NAD+, Rapamycin, Sermorelin, and Metformin.

Score Breakdown

Value25%
5.5
Effectiveness25%
7
User Experience15%
7
Trust & Safety15%
6
Accessibility10%
7
Support10%
6.5
Starting from $250/mo
Visit Arc-1
98

TMates

Best for: nationwide compounded GLP-1 availability including Puerto Rico

6.3

TMates is a Miami-based telehealth platform offering compounded semaglutide ($199/mo) and tirzepatide ($297/mo) across all 50 states plus Puerto Rico, operating on a messaging-first model with independent licensed prescribers and third-party compounding pharmacies.

Score Breakdown

Value25%
7
Effectiveness25%
6
User Experience15%
6
Trust & Safety15%
5
Accessibility10%
8
Support10%
6
Starting from $199/mo
Visit TMates
99

GetRelief Rx

Best for: buyers specifically seeking sublingual (non-injectable) compounded GLP-1 drops who understand the bioavailability trade-offs and lack of human PK data for this formulation

6.1

Get Relief RX, LLC (getreliefrx.com) is a Billings, Montana-based telehealth offering compounded SUBLINGUAL semaglutide (6mg, 9mg) and compounded SUBLINGUAL tirzepatide (7.5mg, 13mg, 16mg). NPI 1306697834. BBB accredited (A rating, March 2026). Free online assessment by licensed provider. Multi-state operations (20+ states). Sublingual drops only — no injectable or FDA-approved brand-name options.

Score Breakdown

Value25%
6.5
Effectiveness25%
5.5
User Experience15%
7
Trust & Safety15%
5
Accessibility10%
6.5
Support10%
6.5
Starting from $269/mo
Visit GetRelief Rx
100

T2D.com

Best for: diabetic GLP-1 access

6.1

T2D.com offers a complete service for compounded semaglutide and tirzepatide that includes the prescriber, medication, and home delivery in one integrated solution. A subsidiary of Vertical Insight Corp, the program is built specifically for individuals managing type 2 diabetes and pre-diabetes.

Score Breakdown

Value25%
5
Effectiveness25%
7
User Experience15%
6
Trust & Safety15%
6.5
Accessibility10%
5.5
Support10%
7
Starting from $999/mo
Visit T2D.com
101

AM Rx

Best for: patients with insurance seeking brand-name GLP-1 access (review regulatory warnings carefully)

5.9

AM Rx (getamrx.com) is a telehealth platform operated by FitRX, LLC (also operates Zealthy and FitRx). Offers compounded semaglutide from $151/mo quarterly and brand-name GLP-1s (Ozempic, Wegovy, Zepbound, Mounjaro) with insurance coordination as low as $25/mo. Video and async consultations available. HSA/FSA accepted.

Score Breakdown

Value25%
6
Effectiveness25%
7
User Experience15%
6
Trust & Safety15%
4
Accessibility10%
7
Support10%
4.5
Starting from $151/mo
Visit AM Rx
102

Direct Meds

Best for: listed for transparent disclosure — see FDA warning and BBB complaint pattern before considering

5.4

Direct Meds is a Utah-based telehealth provider offering compounded semaglutide and tirzepatide in injection and sublingual formats. Listed here with full disclosure of a September 2025 FDA warning letter for misleading marketing, plus a documented pattern of customers reporting unexpected 3-month commitment charges — see warnings and cons before considering.

Score Breakdown

Value25%
6
Effectiveness25%
6
User Experience15%
5
Trust & Safety15%
4
Accessibility10%
6
Support10%
5
Starting from $249/mo
Visit Direct Meds
103

Zealthy

Best for: not currently recommended — listed for transparency and reader awareness only

4.8

Zealthy (legal entity FitRX, LLC, recently renamed to Gronk Inc.) offers compounded semaglutide and tirzepatide via an asynchronous telehealth model. Listed here for completeness with full disclosure of two FDA warning letters and active federal litigation — see warnings and cons sections before considering.

Score Breakdown

Value25%
5
Effectiveness25%
5
User Experience15%
5
Trust & Safety15%
3
Accessibility10%
6
Support10%
5
Starting from $286/mo
Visit Zealthy

Frequently Asked Questions

Sources & methodology — as of April 2026
  1. 1.Weight Loss Rankings — GLP-1 Pricing Index 2026 (our independent dataset)WeightLossRankings.org.
  2. 2.FDA — Compounding and the 503A Pharmacy FrameworkU.S. Food & Drug Administration.
  3. 3.FDA — Drug Shortages Database (current shortage listings)U.S. Food & Drug Administration.
  4. 4.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)New England Journal of Medicine.PMID: 33567185.
  5. 5.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)New England Journal of Medicine.PMID: 40334173.